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齿龈内阿米巴对大白鼠牙龈组织的致病作用
引用本文:胡群,贺智慧,王焱.齿龈内阿米巴对大白鼠牙龈组织的致病作用[J].中国病原生物学杂志,2011(1).
作者姓名:胡群  贺智慧  王焱
作者单位:内蒙古民族大学医学院;
摘    要:目的观察齿龈内阿米巴(Eg)对实验动物的致病作用,了解其发病机制,研究Eg感染与牙周病的关系。方法从牙周病患者的牙周袋内容物分离Eg虫株并培养,分组人工感染大白鼠,观察Eg、共生菌(sb)和生理盐水的致病作用以及组织病理改变。结果Eg组s、b组及生理盐水对照组大白鼠牙周组织炎症发病率分别为87.50%、68.75%和12.50%,差异有统计学意义(P<0.01)。结论宿主免疫力低下时,Eg感染可导致牙龈组织炎症发生。

关 键 词:齿龈内阿米巴  共生菌  致病作用  牙周病  

Studies on the pathogenicity of Entamoeba gingivalis in the adult rat gingiva
HU Qun,HE Zhi-hui,WANG Yan.Studies on the pathogenicity of Entamoeba gingivalis in the adult rat gingiva[J].Journal of Pathogen Biology,2011(1).
Authors:HU Qun  HE Zhi-hui  WANG Yan
Institution:HU Qun,HE Zhi-hui,WANG Yan(Medical College,Inner Mongolia University for the Nationalities,Tongliao 028000,Inner Mongolia,China)
Abstract:Objective To observe the pathogenic effect of Entamoeba gingivalis on experimental animals and to determine its pathogenesis and the relationship between E.gingivalis infection and periodontal disease.Methods E.gingivalis strains were isolated from the contents of the periodontal pocket of patients with periodontal disease and were then cultured.The isolated E.gingivalis strains were used to artificially infect rats in different groups to observe the pathogenic effect of E.gingivalis and symbiotic bacteria(...
Keywords:Entamoeba gingivalis  symbiotic bacteria  pathogenic effect  periodontal disease  
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