| 突触可塑性在血管性认知障碍中的作用 |
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| 引用本文： | 黄自丽,王本孝,许平,黄修燕.突触可塑性在血管性认知障碍中的作用[J].国际脑血管病杂志,2004,17(1):386-389. |
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| 作者姓名： | 黄自丽 王本孝 许平 黄修燕 |
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| 作者单位： | 皖南医学院附属弋矶山医院神经内科,芜湖,241001;上二海交通大学附属第六人民医院普外科,200233; |
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| 摘 要： | 突触损伤在血管性认知障碍(vascular cognitive impairment, VCT)发病的早期即存在,与认知功能障碍关系密切,其具体机制尚不明确.研究突触形态结构的可塑性、突触传递效能的可塑性以及突触蛋白在VCI发病中的作用和机制,有助于进一步阐明VCI的发病机制,从而更有效地防治VCI.
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| 关 键 词： | 脑血管障碍 认知障碍 神经元可塑性 突触囊泡蛋白 |
The role of synaptic plasticity in vascular cognitive impairment |
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| HUANG Zi-li,HUANG Xiu-yan,WANG Ben-xiao,XU Ping.The role of synaptic plasticity in vascular cognitive impairment[J].International Journal of Cerebrovascular Diseases,2004,17(1):386-389. |
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| Authors: | HUANG Zi-li HUANG Xiu-yan WANG Ben-xiao XU Ping |
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| Abstract: | Synaptic injury exists in the early period of vascular cognitive impairment (VCI), and it is closely correlated with the cognitive dysfunction, however, its specific mechanism remains unclear. To study the plasticity of synaptic morphological structure, the plasticity of the efficiency of synaptic transmission as well as the role and mechanism of synapic proteins in the onset of VCI will help to further clarify the pathogenesis of VCI, and thus more effectively combat VCI. |
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| Keywords: | cerebrovascular disorderscognition disordersneuronal plasticitysynaptophysin |
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