PCI治疗慢性心力衰竭合并冠心病患者的疗效及预后分析

目的 研究经皮冠状动脉介入诊疗术(PCI)治疗慢性心力衰竭(心衰)合并冠状动脉粥样硬化性心脏病(冠心病)患者的疗效及长期预后.方法 入选2016年2月至2018年12月于首都医科大学附属北京胸科医院、解放军总医院第七医学中心因慢性心力衰竭住院的患者180例,入院后给予心衰指南指导下的药物治疗(GDMT).上述患者均经冠...

Efficacy and prognosis of PCI in patients with chronic heart failure complicated with coronary heart disease

Objective To study the efficacy and long-term prognosis of percutaneous coronary intervention(PCI)in patients with chronic heart failure complicated with coronary heart disease.Methods One hundred eighty patients hospitalized for chronic heart failure in Beijing Chest Hospital Affiliated to Capital Medical University and army general hospital were selected from February 2016 to December 2018.After admission,they were given drug treatment(GDMT)under the guidance of heart failure guidelines.The 180 patients were identified as left primary artery disease,multivessel disease,proximal anterior descending artery disease or chronic occlusive disease by coronary angiography.PCI revascularization was successfully performed in these patients.Plasma N-terminal pro-brain natriuretic peptide(NT proBNP),left ventricular ejection fraction(LVEF),6-minute walking distance and NYHA cardiac function grade were recorded;The patients were followed up outside the hospital for 24 months.They were followed up once at the first month,six months,12 months and 24 months,respectively.The above indexes were re-recorded to compare whether the difference between the indexes before and after PCI was statistically significant.At the end of follow-up,the number of rehospitalization,all-cause death and cardiac death caused by heart failure were recorded.Results Compared with before operation,LVEF,NYHA and 6-minute walking distance were significantly increased at the 24th month after operation,and NT proBNP was significantly lower than before operation(P<0.01);At the end of follow-up,the number of rehospitalization caused by heart failure was 35(19.4%),the number of cardiac death was 21(11.7%),and the number of all-cause death was 27(15%),which were lower than those reported abroad.Conclusion Based on full GDMT,PCI can effectively improve the heart function of chronic heart failure patients with coronary heart disease and improve exercise tolerance and quality of life;it can minimize readmission rates for heart failure、all cause death and cardiac death.