冠状动脉无复流现象的当前认识

经皮冠状动脉介入治疗（PCI）是急性ST段抬高性心肌梗死患者的首选治疗策略。虽然PCI后冠脉血流恢复，但仍经常观察到无复流现象，并且与较差的临床预后有关。导致该现象的病因机制复杂且相互关联，对这些机制的进一步认识有助于制定个性化的预防和治疗策略。可以使用冠脉造影、心肌对比超声及心脏磁共振等技术诊断无复流。许多药物可能改善实验室和临床无复流，但一些药物尚未明确地改善临床结果。

Current understanding of no-reflow phenomenon

Primary percutaneous coronary intervention (PCI) is the preferred treatment for ST segment elevation myocardial infarction. Although there is restoration of coronary flow after PCI, no-reflow phenomenon is frequently observed and may lead to poor prognosis. The pathogenic mechanisms that cause this phenomenon are complex and interrelated. A better understanding of these mechanisms could promote the development of individualized prevention and treatment strategies. Diagnosis of ‘no-reflow’ can be made using angiography, myocardial contrast echocardiography or cardiovascular magnetic resonance. A number of drugs may improve no-reflow experimentally and clinically, but some have not yet been associated with conclusive improvements in clinical outcome.