基于个性化延续护理模式干预对2型糖尿病合并冠心病患者焦虑抑郁及血管内皮功能的影响

目的探讨个性化延续护理模式干预对2型糖尿病合并冠心病患者焦虑抑郁及血管内皮功能的改善作用。 方法选取2019年5月至2020年10月在茂名市人民医院接受治疗的2型糖尿病合并冠心病的60例患者作为研究对象，随机分为处理组和对照组，每组30例，对照组采用常规的护理，处理组则采用个性化延续护理模式，比较两组患者干预前和干预6个月后的焦虑自评量表（SAS）评分和抑郁自评量表（SDS）评分、血清超敏C反应蛋白（h-CRP）、白细胞介素-6（IL-6）、白细胞介素-10（IL-10）、一氧化氮（NO）、血管内皮生长因子（VEGF）及内皮素-1（ET-1）的表水平。 结果干预6个月后处理组其SAS和SDS评分显著低于对照组（P<0.05），处理组6个月后患者的h-CRP、IL-6显著低于对照组，而IL-10显著高于对照组（P<0.05）；处理组6个月后患者的NO、VEGF显著高于对照组，而ET-1显著低于对照组，差异具有统计学意义（P<0.05）。 结论基于个性化延续护理模式是一种有效促进2型糖尿病合并冠心病患者缓解焦虑抑郁情绪，改善患者内皮功能的护理方式。

Effect of intervention based on personalized continuous nursing model on anxiety,depression and vascular endothelial function in patients with type 2 diabetes and coronary heart disease

ObjectiveTo explore the effect of personalized continuous nursing intervention on anxiety, depression and vascular endothelial function in patients with type 2 diabetes and coronary heart disease. MethodsA total of 60 patients with type 2 diabetes and coronary heart disease in Maoming People's Hospital from May 2019 to October 2020 were selected as the research objects. They were randomly divided into a treatment group and a control group, with 30 cases in each group. The control group received routine care, while the treatment group received Adopt personalized continuous care model. The SAS and SDS scores, serum h-CRP, IL-6, IL-10, NO, VEGF and ET-1 levels of the two groups were compared before intervention and after 6 months of intervention. ResultsAfter 6 months of intervention, the SAS and SDS scores of the treatment group were significantly lower than those of the control group (P<0.05), and the h-CRP and IL-6 of the treatment group were significantly lower than those of the control group, while IL-10 was significantly higher. Compared with the control group (P<0.05); after 6 months in the treatment group, the NO and VEGF of the patients were significantly higher than the control group, while ET-1 was significantly lower than the control group, the difference was statistically significant (P<0.05). ConclusionsPersonalized continuation of nursing is a nursing method that effectively promotes the relief of anxiety and depression in patients with type 2 diabetes and coronary heart disease and improves the endothelial function of patients.