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经胸超声心动图联合多层螺旋CT对肺高压患者的临床评估分析
引用本文:徐杰,史阳阳,史薪玮,孙凯.经胸超声心动图联合多层螺旋CT对肺高压患者的临床评估分析[J].临床肺科杂志,2022,27(3):336-341.
作者姓名:徐杰  史阳阳  史薪玮  孙凯
作者单位:210000 江苏 南京,南京医科大学第一附属医院急诊科
基金项目:国家自然科学基金(No.81871544);江苏省自然科学基金(No.BK20181493)。
摘    要:目的依据多层螺旋CT(Multislice spiral CT,MSCT)及经胸超声心动图(Transthoracic echocardiography,TTE)分析肺高压患者的临床特征,探讨与疾病严重程度的相关性。方法收集我院2018年8月至2021年1月经TTE评估为肺高压的83名患者的临床资料作为实验组,同期收集78例我院健康体检的临床资料作为对照组。纳入患者MSCT、TTE、心肌生化指标、临床表现、既往病史等,对病情严重程度综合评估。结果①MSCT与TTE各测量指标间存在显著相关性。②PASP分级重度患者与轻、中度患者相比,WHO分级4级患者与WHO分级1~2级的患者相比,MSCT结果显示dMPA、rPA及RVD/LVD均显著升高。TTE结果显示,RAD/LAD,RVDd/LVDd同样显著增加,且各组间差异具有统计学意义。③MSCT测量的dMPA及rPA对PASP严重程度有较好预测价值。④TTE测量RVDd、MSCT测量rPA及有无糖尿病史是PASP升高的危险因素。结论①对于PH严重程度的评估,TTE和MSCT都具有较高价值。②对于初诊时PASP较高、WHO评分较高的肺高压患者,常提示患者病情危重,应密切注意其病情改变。③TTE测量RVDd、MSCT测量rPA及有无糖尿病史是病情加重的危险因素。

关 键 词:肺高压  多层螺旋CT  主肺动脉内径

Clinical evaluation and analysis of transthoracic echocardiography combined with multislice spiral CT in pa-tients with pulmonary hypertension
XU Jie,SHI Yang-yang,SHI Xin-wei,SUN Kai.Clinical evaluation and analysis of transthoracic echocardiography combined with multislice spiral CT in pa-tients with pulmonary hypertension[J].Journal of Clinical Pulmonary Medicine,2022,27(3):336-341.
Authors:XU Jie  SHI Yang-yang  SHI Xin-wei  SUN Kai
Institution:(Emergency Department,The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210000,China)
Abstract:Objective To analyze the clinical characteristics of patients with pulmonary hypertension based onMultislice spiral CT(MSCT)and Transthoracic echocardiography(TTE),and to explore the correlation with disease severity.Methods The clinical data of 83 patients with pulmonary hypertension assessed by TTE treated in our hospital from August 2018 to January 2021were collected as the experimental group.During the same period,78 clinical data of health examinations in our hospital were collected as the control group.MSCT,TTE,myocardial biochemical indicators,clinical manifestations,and past medical history were all included to comprehensively evaluate the severity of the disease.Results①There was a significant correlation between MSCT and TTE measurement indicators.②Compared with patients with mild and moderate patients and WHO classification 1~2,patients with severe PASP classificationand WHO classification 4 showed MSCT results with dMPA,rPA,and RVD/LVD,and TTE results with significantly increased RAD/LAD and RVDd/LVDd,and the differences between groups were statistically significant.③The dMPA and rPA measured by MSCT had good predictive value for the severity of PASP.④RVD dmeasuredby TTE,rPA measured by MSCT,and a history of diabetes were risk factors for elevated PASP.Conclusion①For the assessment of the severity of PH,both TTE and MSCT have a high value.②For patients with pulmonary hypertension with a high PASP and a high WHO score at the first diagnosis,it is often suggested that the patient's condition is critically ill,and should be given close attention.③RVD dmeasured by TTE,rPA measured by MSCT,and a history of diabetes were are risk factors for increased exacerbations.
Keywords:Pulmonary arterial hypertension  MSCT  Inner diameter of the main pulmonary arter
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