| 血浆NT-proBNP水平对脓毒症合并心肌损伤的诊断价值 |
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| 引用本文： | 贺红霞,胡苏萍,黄毅.血浆NT-proBNP水平对脓毒症合并心肌损伤的诊断价值[J].临床肺科杂志,2011,16(4):523-524. |
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| 作者姓名： | 贺红霞 胡苏萍 黄毅 |
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| 作者单位： | 武汉,武汉大学人民医院呼吸内科,湖北,430060 |
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| 摘 要： | 目的观察N-末端B型利钠肽原（NT-proBNP）在脓毒症及其脓毒症合并心肌损伤患者的水平变化。方法武汉大学人民医院住院的脓毒症患者37例,其中并心肌损伤者17例（A组）,非心肌损伤者20例（B组）,健康对照者20例（C组）。测定入院后24 h内血浆NT-proBNP水平及肌钙蛋白I的水平,对比各组之间血浆NT-proBNP水平,并将NT-proBNP水平与肌钙蛋白I进行相关性分析。结果 A、B、C组NT-proBNP水平入院后分别为（3180.6±1420.57）pg/ml,（746.66±225.63）pg/ml,（60.195±28.305）pg/ml。对比各组入院后NT-proBNP的水平,有统计学意义（P〈0、01）。且脓毒症并心肌损伤组肌钙蛋白I为3.8822±1.8221 ng/ml,与NT-proBNP成正相关。结论 NT-proBNP在脓毒症患者血浆中水平升高,且在心肌损伤组与非心肌损伤组中有差异,血浆NT-proBNP与肌钙蛋白I成正相关,两者升高越明显病情越危重,可作为判断心肌是否受损的指标。
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| 关 键 词： | N-末端B型利钠肽原 肌钙蛋白I 脓毒症 心肌损伤 |
Diagnostic value of plasma N-terminal pro-B-type natriuretic peptide(NT-proBNP) in patients with sepsis combined with myocardial injury |
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| HE Hong-xia,HU Su-ping,HUANG Yi.Diagnostic value of plasma N-terminal pro-B-type natriuretic peptide(NT-proBNP) in patients with sepsis combined with myocardial injury[J].Journal of Clinical Pulmonary Medicine,2011,16(4):523-524. |
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| Authors: | HE Hong-xia HU Su-ping HUANG Yi |
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| Institution: | HE Hong-xia,HU Su-ping,HUANG Yi Department of Respiratory Medicine,Remin Hospital of Wuhan University,Wuhan430060,China |
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| Abstract: | Objective To observe the variation of NT-proBNP level in patients with sepsis and sepsis combined with myocardial injury.And search for the early diagnostic index of myocardial injury.MethodsWe recruited 37 patients received a diagnosis of sepsis according to the diagnosis and treatment program of septicemia in 2003 by the American College of Chest Physicians and the Society of Critical Care Medicine(ACCP/SCCM).The 37 cases were divided into myocardial injury group(group A) and non-myocardial injury group(g... |
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| Keywords: | NT-proBNP troponin I sepsis myocardial injury |
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