| 系统性红斑狼疮并发肺动脉高压1例并文献复习 |
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| 引用本文： | 陆国军,王彤,李梅梅,吴睿,殷凯生.系统性红斑狼疮并发肺动脉高压1例并文献复习[J].临床肺科杂志,2008,13(6):714-715. |
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| 作者姓名： | 陆国军 王彤 李梅梅 吴睿 殷凯生 |
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| 作者单位： | 南京医科大学第一附属医院呼吸科,210029 |
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| 摘 要： | 目的提高对系统性红斑狼疮（SLE）并发肺动脉高压（PHT）的发病机制、临床表现、治疗及预后的认识。方法对1例并发PHT的SLE病例进行分析和讨论，并结合相关文献复习。结果SLE并发PHT的机制尚不明确。其临床表现无特异性，早期症状多为呼吸困难。SLE患者出现雷诺征时，应高度怀疑PHT的存在。大剂量糖皮质激素联合免疫抑制剂可显著降低PHT。结论SLE并发PHT常提示预后不良，应尽早诊断及治疗。针对原发病的强化治疗可有效降低PHT。
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| 关 键 词： | 系统性红斑狼疮 肺动脉高压 临床分析 治疗方法 |
| 修稿时间： | 2007年12月5日 |
Systemic lupus erythematosus with pulmonary hypertension: a case report and review of the literature |
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| Institution: | LU Guo- jun, WANG Tong, LI Mei-mei, et al(Department of Respiratory Medicine, The First Affiliated Hospital of Nanfing Medical University, Nanjing 210029, China) |
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| Abstract: | Objective To describe the pathogenesis, clinical symptoms, and therapeutic management of SLE with PHT. Meth. ods A case of SLE with PHT was report. The clinical features of other cases from related literature were reviewed. Results The pathogenesis of SLE with PHT was uncertain. And it had no specific clinical symptoms. Dyspnea was common early symptom. It is suggested that to doubt the existence of PHT or not when SLE have Raynaund＇s phenomenon（RP）, large dose of glucocorticostereid and immunosuppressant can depress PHT significandy. Conclusions SLE with PHT is an adverse prognostic sign, should be early diagnose and treat. Intensive treatment on its cause can efficiently cut down PHT. |
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| Keywords: | SLE Pulmonary hypertension |
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