| MMEF/FVC及其下降值与支气管激发试验阳性率的关系探讨 |
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| 引用本文： | 陈正贤,马丽平.MMEF/FVC及其下降值与支气管激发试验阳性率的关系探讨[J].临床肺科杂志,2010,15(5):617-618. |
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| 作者姓名： | 陈正贤 马丽平 |
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| 作者单位： | 1. 广州,广东省医学科学院,广东省人民医院呼吸内科,广东,510080
2. 广州,南方医科大学研究生学院,广东,510515 |
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| 摘 要： | 目的探讨MMEF/FVC及其下降值与支气管激发试验阳性率的关系。方法235例慢性咳嗽、胸闷、喘息的患者进行组织胺支气管激发试验,并分析支气管激发试验结果阳性率与患者基础肺功能MMEF/FVC及其下降值的关系。结果在支气管激发试验阳性组MMEF/FVC比值明显低于阴性组(0.87+0.76,1.01+0.28;P0.001),差异有统计学意义,并且MMEF/FVC比值在不同激发程度的下降值同样具有统计学意义(P0.05),ROC曲线下面积为72%(标准误为0.033,P0.001),MMEF/FVC比值的最佳截点为0.85,灵敏度67%(75/112),特异度70%(86/123),,准确率为68.5%(161/235),阳性预测值为67%,阴性预测值为70%。结论支气管激发试验阳性率与MMEF/FVC比值及其下降有关,并且此比值可用于预测支气管激发试验阳性率。
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| 关 键 词： | 支气管激发试验 肺功能 气道反应性 |
Discuss the relation between MMEF/FVC and its decline and positive rate of bronchial provocation tests |
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| CHEN Zheng-xian,MA Li-ping.Discuss the relation between MMEF/FVC and its decline and positive rate of bronchial provocation tests[J].Journal of Clinical Pulmonary Medicine,2010,15(5):617-618. |
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| Authors: | CHEN Zheng-xian MA Li-ping |
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| Institution: | . (Department of Respiratory Medicine, People＇s Hospital of Guangdong Province 510080, China ; Graduate School, Northern Medical University, China ) |
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| Abstract: | Objective To study the relationship between MMEF/FVC and its decline and positive rate of bronchial provocation tests.Methods A total of 235 patients with chronic cough,choking sensation in chest,and gasp underwent bronchial provocation tests.The relation between MMEF/FVC and its decline and positive rate of bronchial provocation tests was analyzed.Results The subject in the positive group had significantly lower MMEF/FVC value than that in the negative group in bronchial provocation test(0.87+0.76,1.01+0.2... |
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| Keywords: | bronchial provocation test pulmonary function airway responsiveness |
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