如何开展高质量的结核病诊断准确性研究

结核病诊断常涉及多种方法或检查,这使得基于日常工作开展结核病诊断准确性研究成为可能。但目前多数结核病诊断准确性研究仍存在质量问题,如研究对象选择、金标准核实、盲法评价等,这就需要研究者进行严谨的设计和规范的报告。为此,笔者系统地介绍了诊断准确性研究的设计、分析指标及实施过程中应注意的问题,从而为开展高质量的原始研究提供帮助。

How to conduct a high-quality study on a tuberculosis diagnostic research

Tuberculosis diagnosis often involved a variety of methods or examinations that makes it possible to conduct tuberculosis diagnostic accuracy studies based on routine work. However, most of the current diagnostic accuracy of tuberculosis research still have quality problems, such as patients’ selection, gold standard verification, blind evaluation, and so on. All these requires researchers to rigorous design, standardized report. So, this paper systematically introduces the design of diagnostic accuracy, indicators analysis and some problems need to pay attention, and help researchers to carry out high-quality original research.