某医院HIV感染者中HBV HCV TP混合感染状况分析

目的了解综合性医院首诊艾滋病病毒(HIV)感染者中合并乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和梅毒螺旋体(TP)的混合感染情况及临床特点,为艾滋病(AIDS)的防控和治疗提供科学依据。方法2013年1月至2017年12月,以非艾滋病首诊于某综合性医院而确证为HIV感染者,收集其人口学资料和临床资料,并进行乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒抗体(HCV-Ab)和梅毒特异性抗体(TP-Ab)检测。结果共确证359例HIV感染者,其年龄中位数为45岁(2~86岁),男性251人(69.92%),女108人(30.08%)。15例(4.18%)通过母婴途径感染,122例(33.98%)通过性途径感染和222例(61.84%)通过血液(单采血浆)途径感染。混合感染中,35例(9.75%)感染HBV,63例(17.55%)感染HCV,57例(15.88%)感染TP。HIV感染的不同途径中,HBV、HCV和TP的混合感染率存在差异。HIV感染者首诊科室共涉及26个,其中15个内科相关科室,4个外科相关科室,7个其他科室。涉及疾病谱18类,主见呼吸系统疾病、感染性疾病、神经系统疾病、消化系统疾病、血液系统疾病。结论首诊综合性医院的HIV感染者中合并HBV、HCV和TP感染率相对较高,涉及就诊科室多,疾病谱广。

Prevalence of HIV patients co-infected with HBV,HCV and TP in the general hospital

Objective To study the status and characteristics of human immune deficiency virus(HIV)patients coinfected with hepatitis B virus(HBV),hepatitis C virus(HCV)and treponema pallidum(TP)in the general hospital so as to provide scientific evidence for further control and treatment.Methods The demographic and clinical data of HIV patients were collected from January 2013 to December 2017 in the general hospital they first visited.HIV patients were tested with HBsAg,HCV-Ab and TP-Ab.Results 359 HIV patients participated in the study and 15(4.18%)infected with HIV through mother to child transmission,122(33.98%)through sexual transmission,and 222(61.84%)through blood transmission.Their median age was 45(2-86)years old,with 69.92%male.A total of 26 clinical departments were involved in the first diagnosis of HIV infection,including 15 internal medicine departments,4 surgical departments and 7 others.The spectrum of diseases mainly included respiratory disease,infectious diseases,nervous system diseases,digestive system diseases,and hematological diseases.Conclusion The prevalence of HIV patients co-infected HBV,HCV and/or TP is relatively high.HIV patients in the general hospital they first visited seek medical care in different clinical departments and the spectrum of diseases is various.