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西安地区中老年人的痴呆患病率调查
引用本文:屈秋民,乔晋,杨剑波,韩建峰,罗国刚,张辉,武成斌,王小娟,霍东红,杨华,李正仪,邓美英,韩雪梅,赵松珍,于普林,张振馨.西安地区中老年人的痴呆患病率调查[J].中华老年医学杂志,2001,20(4):283-286.
作者姓名:屈秋民  乔晋  杨剑波  韩建峰  罗国刚  张辉  武成斌  王小娟  霍东红  杨华  李正仪  邓美英  韩雪梅  赵松珍  于普林  张振馨
作者单位:1. 西安交通大学第一医院神经内科
2. 公共卫生学院
3. 卫生部北京医院
4. 北京协和医院神经科
基金项目:国家"九五”攻关资助课题(96-906-05-01)
摘    要:目的:了解西安载我中老年人痴呆的流行现状。方法:E要用多分层,多级,随机、整群抽样、以简易智能状态量表(MMSE)为筛查工具,对西安地区4850例5及以上中老年人进行了痴呆患病率调查。结果:符合美国精神疾病诊断和统计手册第4版(DSM-Ⅳ)和美国国立神经病学、语言交流障碍和卒中-老年性痴呆 关疾病学会(NINCDS-ADRDA)痴呆诊断标准者171例,痴呆患病率3.53%。其中Alzheimer痴呆(AD)100例,患病率2.06%,占58.48%,血管性痴呆(VD)54例,患病率1.11%,占31.58%,痴呆及VD患病率男女间差异无显著性P>0.05),而AD患病率女性明显高于男性(P<0.01)。痴呆及AD、VD、患病率均随增龄而显著增高(P<0.01),年龄每增长5岁,患病率约增高1倍。文盲组痴呆及AD患病率高于小学和初中以上组(P<0.01)。各职业之间痴呆及AD、VD患病率用年龄分层后差异均无显著性(P>005)。城市和农村痴呆、AD、VD患病率差异亦无显著性(P>0.05)。结论:我国痴呆患病率并不低,基本与欧美国家持平,高龄、女性、低文化水平,能是AD的危险因素。

关 键 词:痴呆  阿尔茨海默病  危险因素  患病率  调查  西安地区
修稿时间:2001年1月3日

Study of the prevalence of senile dementia among elderly people in Xi'an, China
QU Qiumin ,QIAO Jin,YANG Jianbo,et al..Study of the prevalence of senile dementia among elderly people in Xi''''an, China[J].Chinese Journal of Geriatrics,2001,20(4):283-286.
Authors:QU Qiumin  QIAO Jin  YANG Jianbo  
Institution:QU Qiumin *,QIAO Jin,YANG Jianbo,et al. *?Department of Neurology,First Hospital of Xi'An JiaoTong University,Xi'an 710061,China
Abstract:Objective In order to explore the prevalence of senile dementia among elderly people in Xi'an, China population aged 55 years and over was investigated from September 1997 to December 1998. Methods 4 850 residents (aged 55 years and over) were studied in urban and rural areas in Xi'an by stratified multi stage cluster sampling method with the Mini Mental State Examination (MMSE) as screening tool and DSM IV and NINCDS ADRDA as clinical diagnostic criteria. Results The prevalence of total dementia was 3 53%(171 patients); the prevalence of Alzheimer's disease (AD) and vascular dementia (VD) was 2 06%(100 patients) and 1 11%(54 patients) ( P >0 05) , repectively. Of all dementia, AD and VD accounted for 58 48% and 31 58%, respectively. The AD prevalence in female was higher than that in male( P <0 01), but there was no statistical difference between female and male in the prevalence in total dementia and VD( P >0 05). The prevalence of total dementia, AD and VD tended to increase with aging( P <0 01)and showed no statistical difference among all occupations when stratified with age( P >0 05). The prevalence of dementia increased one fold every five year of age increasing. The prevalence of dementia and AD in illiterate group was higher than in educated people with elementary school level and above junior high school level ( P <0 01). Conclusions The prevalence of dementia in China is not lower than that in other countries and it is basically equal to that in European and American countries. AD is one of the main causes of dementia. Senility, lower educational level and female elders seemed to be risk factors of AD.
Keywords:Dementia  Alzheimer disease  Risk factor
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