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原发性胆汁性肝硬化伴甲状旁腺腺瘤诊治
引用本文:王保平,张洁,朱梅,田伟军,崔瑾,苏文凌,朱铁虹,邱明才.原发性胆汁性肝硬化伴甲状旁腺腺瘤诊治[J].中华内分泌代谢杂志,2011,27(10).
作者姓名:王保平  张洁  朱梅  田伟军  崔瑾  苏文凌  朱铁虹  邱明才
作者单位:1. 300052,天津医科大学总医院内分泌科
2. 天津医科大学总医院消化科
3. 天津医科大学总医院普外科
摘    要:原发性胆汁性肝硬化可从多种途径影响钙和维生素D的代谢,进而引起骨软化和继发性甲状旁腺功能亢进症,但当同时出现低蛋白血症时可掩盖血钙的真实水平.因此若该病合并甲状旁腺腺瘤时容易漏诊.本文详细介绍1例原发性胆汁性肝硬化合并甲状旁腺腺瘤的诊治过程,旨在提醒临床医生重视低蛋白血症对血清总钙水平的影响.

关 键 词:原发性胆汁性肝硬化  继发性甲状旁腺功能亢进症  低蛋白血症  血钙  甲状旁腺腺瘤

Appoach to the patient with parathyroid adenoma and primary biliary cirrhosis;diagnosis and treatment
WANG Bao-ping,ZHANG Jie,ZHU Mei,TIAN Wei-jun,CUI Jin,SU Wen-ling,ZHU Tie-hong,QIU Ming-cai.Appoach to the patient with parathyroid adenoma and primary biliary cirrhosis;diagnosis and treatment[J].Chinese Journal of Endocrinology and Metabolism,2011,27(10).
Authors:WANG Bao-ping  ZHANG Jie  ZHU Mei  TIAN Wei-jun  CUI Jin  SU Wen-ling  ZHU Tie-hong  QIU Ming-cai
Abstract:In patient with primary biliary cirrhosis,the metabolism of calcium and vitamin D could be affected and osteomalacia and secondary hyperparathyroidism might occurr.Besides,hypoalbuminemia may mask the real level of serum calcium and thus lead to misdiagnosis of coexisting parathyroid adenoma.Therefore,a rare case of parathyroid adenoma associated with primary biliary cirrhosis was herewith presented to call attention to the effect of hypoalbuminemia on serum calcium.
Keywords:Primary biliary cirrhosis  Secondary hyperparathyroidism  Hypoalbuminemia  Serum calcium  Parathyroid adenoma
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