| 血糖波动诱导大鼠骨髓出现胰岛样细胞 |
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| 引用本文： | 武晓泓,朱剑,蒋晶晶,徐瑜,刘翠萍,茅晓东,徐宽枫,刘超.血糖波动诱导大鼠骨髓出现胰岛样细胞[J].中华内分泌代谢杂志,2008,24(2). |
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| 作者姓名： | 武晓泓 朱剑 蒋晶晶 徐瑜 刘翠萍 茅晓东 徐宽枫 刘超 |
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| 作者单位： | 南京医科大学第一附属医院内分泌科,210029 |
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| 摘 要： | 本研究采用腹腔注射葡萄糖诱导SD大鼠血糖波动模型,发现骨髓中出现胰岛素、C肽、胰高血糖素、生长抑素和胰淀粉样多肽阳性细胞团簇,并表达胰岛发育和功能相关基因.
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| 关 键 词： | 血糖波动 骨髓 胰岛样细胞 大鼠 |
Glycemic excursion-induced islet-like cells in rat bone marrow |
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| WU Xiao-hong,ZHU Jian,JIANG Jing-jing,XU Yu,LIU Cui-ping,MAO Xiao-dong,XU Kuan-feng,LIU Chao.Glycemic excursion-induced islet-like cells in rat bone marrow[J].Chinese Journal of Endocrinology and Metabolism,2008,24(2). |
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| Authors: | WU Xiao-hong ZHU Jian JIANG Jing-jing XU Yu LIU Cui-ping MAO Xiao-dong XU Kuan-feng LIU Chao |
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| Abstract: | Glycemic excursion was induced in SD rats by intraperitoneal injection of 50% glucose solution, and cells isolated from bone marrow of these rats showed cell clusters which expressed insulin, c-peptide, glucagon, somatostatin and islet amyloid polypeptide, and other genes related to islet-cells development and functions. |
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| Keywords: | Sprague-Dawley |
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