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| 2型糖尿病患者内脂素水平与颈动脉内中膜厚度相关 | |
| 引用本文： | 高丽华,赵占胜,田晖,吴冰洁,贾丽梅,王绵,邓永贵,周红,张力辉,苏胜偶.2型糖尿病患者内脂素水平与颈动脉内中膜厚度相关[J].中华内分泌代谢杂志,2010,26(1). |
| 作者姓名： | 高丽华 赵占胜 田晖 吴冰洁 贾丽梅 王绵 邓永贵 周红 张力辉 苏胜偶 |
| 作者单位： | 1. 河北医科大学第二医院内分泌科,石家庄,050000 2. 河北医科大学第二医院功能科,石家庄,050000 3. 河北医科大学第二医院体检中心,石家庄,050000 |
| 基金项目： | 河北省二○○七年医学科学研究重点课题计划项目 |
| 摘 要： | 73例2型糖尿病患者,根据颈动脉内中膜厚度(IMT)分为动脉粥样硬化(AS)组和非AS组,测定血浆内脂素水平.结果 显示,2型糖尿病AS组内脂素水平高于非AS组(44.95±10.14对34.52±9.08)μg/L,P<0.05],均高于对照组(24.46±7.18)μg/L,均P<0.05],并与IMT、腰臀比、内脏脂肪厚度、空腹胰岛素、胰岛素抵抗指数呈正相关.年龄、病程、HbA_(1c)及内脂素是影响颈动脉IMT的相关因素. |
| 关 键 词： | 内脂素 糖尿病 2型 动脉粥样硬化 颈动脉内中膜厚度 |
Association between plasma visfatin and intima-media thickness of carotid artery in patients with type 2 diabetes |
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| GAO Li-hua,ZHAO Zhan-sheng,TIAN Hui,WU Bing-jie,JIA Li-mei,WANG Mian,DENG Yong-gui,ZHOU Hong,ZHANG Li-hui,SU Sheng-ou.Association between plasma visfatin and intima-media thickness of carotid artery in patients with type 2 diabetes[J].Chinese Journal of Endocrinology and Metabolism,2010,26(1). | |
| Authors: | GAO Li-hua ZHAO Zhan-sheng TIAN Hui WU Bing-jie JIA Li-mei WANG Mian DENG Yong-gui ZHOU Hong ZHANG Li-hui SU Sheng-ou |
| Abstract: | Seventy-three patients with type 2 diabetes mellitus were divided into atheroselerosis(AS) group and non-AS group according to the intima-media thickness(IMT)of the carotid artery.The plasma visfatin level in AS group was higher than that in non-As group(44.95±10.14 vs 34.52±9.08)μg/L,P<0.05],and both of them were higher than that of the control (24.46±7.18)μg/L,both P<0.05 ].The visfatin level Was positively correlated with IMT,waist-to-hip ratio,visceral fat thickness,fasting insulin,and HOMA insulin resistance index.Age,duration of diabetes,HbA_(1C),and visfatin level were the major risk factors for IMT of the carotid artery. |
| Keywords: | Visfatin Diabetes meilitus type 2 Atherosclerosis Intima-media thickness |
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