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| 一氧化氮合酶在急性胰腺炎大鼠胰岛中的表达 | |
| 引用本文： | 郭子倩,贺丽萍,刘月顺,龙治峰.一氧化氮合酶在急性胰腺炎大鼠胰岛中的表达[J].中华内分泌代谢杂志,2003,19(4):324-325. |
| 作者姓名： | 郭子倩 贺丽萍 刘月顺 龙治峰 |
| 作者单位： | 1. 421001,衡阳,南华大学基础医学院病理生理教研室 2. 421001,衡阳,南华大学基础医学院组胚教研室 3. 421001,衡阳,南华大学基础医学院显微形态中心 |
| 摘 要： | 在SD大鼠以胰胆管结扎法建立急性胰腺炎模型，在急性胰腺炎大鼠胰岛β细胞神经元型一氧化氮合酶(nNOs)表达和血清一氧化氮(N0)水平下降，血清葡萄糖和淀粉酶水平升高，提示急性胰腺炎时内分泌紊乱可能与胰岛β细胞nNOS表达下调有关。 |
| 关 键 词： | 一氧化氮合酶 急性胰腺炎 大鼠 胰岛 表达 |
| 修稿时间： | 2001年12月3日 |
Expression of nitric oxide synthase in rat islets with acute pancreatitis |
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| GUO Zi-qian,HE Li-ping,LIU Yue-shun,LONG Zhi-feng.Expression of nitric oxide synthase in rat islets with acute pancreatitis[J].Chinese Journal of Endocrinology and Metabolism,2003,19(4):324-325. | |
| Authors: | GUO Zi-qian HE Li-ping LIU Yue-shun LONG Zhi-feng |
| Institution: | GUO Zi-qian,HE Li-ping,LIU Yue-shun,LONG Zhi-feng. *Department of Pathophysiology,Preclinical Medical College,Nanhua University,Hengyang 421001 Corresponding author: HE Li-ping,421001 |
| Abstract: | The model of acute pancreatitis was established in SD rats by ligating pancreatic and bile duct. The expression of neuronal nitric oxide synthase (nNOS) and the level of serum nitric oxide were decreased and the levels of serum glucose and amylase were increased in the rats with acute pancreatitis, suggesting that endocrine disturbance in the rats with acute pancreatitis is related to down-regulation of nNOS expression. |
| Keywords: | Pancreatitis Islets of Langerhans Nitic oxide synthase Rats Sprague-Dawley |
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