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| 2型糖尿病非糖尿病一级亲属中肥胖患者血浆内脂素水平 | |
| 引用本文： | 刘军,查英,王芳,陈灶萍,徐炯,盛励,许火根,廖晓寰,郭瑜琳.2型糖尿病非糖尿病一级亲属中肥胖患者血浆内脂素水平[J].中华内分泌代谢杂志,2007,23(4):323-324. |
| 作者姓名： | 刘军 查英 王芳 陈灶萍 徐炯 盛励 许火根 廖晓寰 郭瑜琳 |
| 作者单位： | 1. 200240,上海,复旦大学附属上海市第五人民医院内分泌科 2. 200240,上海,复旦大学附属上海市第五人民医院同位素室 3. 200240,上海,复旦大学附属上海市第五人民医院免疫室 4. 200240,上海,复旦大学附属上海市第五人民医院心血管超声室 |
| 摘 要： | 检测了2型糖尿病一级亲属、单纯肥胖和健康对照者内脂素（visfatin）、内皮依赖性血管舒张功能、颈总动脉内膜中层厚度，并用MRI评价内脏脂肪和皮下脂肪面积。结果提示2型糖尿病一级亲属中肥胖患者和单纯肥胖患者内脂素水平高于2型糖尿病一级亲属非肥胖者和健康对照组，并且内脂素与空腹血糖呈独立负相关。 |
| 关 键 词： | 内脂素 糖尿病 2型 一级亲属 肥胖症 |
| 修稿时间： | 2006-08-22 |
Plasma visfatin level in obese patients of nondiabetic first-degree relatives of type 2 diabetes |
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| LIU Jun,ZHA Ying,WANG Fang,CHEN Zao-ping,XU Jiong,SHENG Li,XU Huo-geng,LIAO Xiao-huan,GUO Yu-ling.Plasma visfatin level in obese patients of nondiabetic first-degree relatives of type 2 diabetes[J].Chinese Journal of Endocrinology and Metabolism,2007,23(4):323-324. | |
| Authors: | LIU Jun ZHA Ying WANG Fang CHEN Zao-ping XU Jiong SHENG Li XU Huo-geng LIAO Xiao-huan GUO Yu-ling |
| Abstract: | The plasma visfatin, endothelium-dependent artery dilation and intima-media thickness of common carotid arteries were measured in first-degree relatives of type 2 diabetes, obese patients and control subjects. Regional body fat were detected by MRI. The result suggested that plasma visfatin levels were significantly higher in obese subjects than those in non-obese subjects, and hypervisfatinemia is independently associated with fasting blood glucose. |
| Keywords: | Visfatin Diabetes mellitus type 2 First-degree relatives Obesity |
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