| 2型糖尿病患者罗格列酮治疗前后血浆胃促生长素水平的变化及其与胰岛素抵抗的关系 |
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| 引用本文： | 高燕明,卢桂芝,蒋秋明,董爱梅,郭晓蕙,高妍,庞永正,唐朝枢.2型糖尿病患者罗格列酮治疗前后血浆胃促生长素水平的变化及其与胰岛素抵抗的关系[J].中华内分泌代谢杂志,2007,23(2):149-150. |
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| 作者姓名： | 高燕明 卢桂芝 蒋秋明 董爱梅 郭晓蕙 高妍 庞永正 唐朝枢 |
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| 作者单位： | 1. 100034,北京大学第一医院内分泌科
2. 100034,北京大学第一医院心血管研究所 |
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| 摘 要： | 探讨2型糖尿病在应用磺酰脲类药物治疗的基础上加用罗格列酮类药物治疗前后血浆胃促生长素水平变化及其与胰岛素抵抗的关系。2型糖尿病患者应用罗格列酮治疗4周及12周血浆胃促生长素水平升高，胰岛素抵抗指数降低。
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| 关 键 词： | 糖尿病 2型 胃促生长素 罗格列酮 |
| 修稿时间： | 2006-07-06 |
Change in plasma ghrelin level and the relation between ghrelin and insulin resistance in type 2 diabetic patients after rosiglitazone therapy |
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| GAO Yan-ming,LU Gui-zhi,JIANG Qiu-ming,DONG Ai-mei,GUO Xiao-hui,GAO Yan,PANG Yong-zheng,TANG Chao-shu.Change in plasma ghrelin level and the relation between ghrelin and insulin resistance in type 2 diabetic patients after rosiglitazone therapy[J].Chinese Journal of Endocrinology and Metabolism,2007,23(2):149-150. |
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| Authors: | GAO Yan-ming LU Gui-zhi JIANG Qiu-ming DONG Ai-mei GUO Xiao-hui GAO Yan PANG Yong-zheng TANG Chao-shu |
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| Institution: | Department of Endocrinology, Peking University First Hospital, Beijing 100034, China |
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| Abstract: | The change in plasma ghrelin level after 4- and 12-week adjunctive therapy of rosiglitazones in type 2 diabetic patients inadequately controlled by sulphonylurea alone was observed and the relation between ghrelin and insulin resistance was analysed. The results showed that rosiglitazones significantly increased circulating ghrelin level and obviously decreased insulin resistance index after therapy for 4 and 12 weeks in type 2 diabetic patients. |
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| Keywords: | Diabetes mellitus type 2 Ghrelin Rosiglitazone |
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