| 冠状动脉内注射替罗非班对急诊冠状动脉介入术中无再流的作用 |
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| 引用本文： | 朱强,刘福元,黎晓兰,朱磊,骆峰,李晓妹,李静,陆莉.冠状动脉内注射替罗非班对急诊冠状动脉介入术中无再流的作用[J].临床心血管病杂志,2011,27(1). |
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| 作者姓名： | 朱强 刘福元 黎晓兰 朱磊 骆峰 李晓妹 李静 陆莉 |
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| 作者单位： | 湖北襄樊市第一人民医院心内科,湖北襄樊,441000 |
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| 摘 要： | 目的:评价血小板Ⅱb/Ⅲa受体拮抗剂替罗非班经冠状动脉注射对急性ST段抬高型心肌梗死(STEMI)患者急诊经皮冠状动脉介入(PCI)治疗后无再流的疗效。方法:STEMI急诊经皮经腔冠状动脉成形术/支架置入术梗死相关动脉再通后存在无再流现象50例。2005-01-2007-10,20例冠状动脉内注射硫氮唑酮(0.5～2.0mg),2007-11-2010-03,30例冠状动脉内注射替罗非班(0.5～1.0mg);注射完后10min行冠状动脉造影,评定冠状动脉血流TIMI分级。结果:硫氮唑酮组应用后20～40min内TIMI血流3级10例,TIMI血流0～2级10例;替罗非班组应用后20～40min内TIMI血流3级24例,TIMI血流0～2级6例。达TIMI3级患者替罗非班组多于硫氮唑酮组(P<0.05)。结论:经冠状动脉给予替罗非班(0.5～1.0mg)后能有效改善急诊PCI术中无再流现象。
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| 关 键 词： | ST段抬高心肌梗死 替罗非班 硫氮唑酮 冠状动脉介入治疗 无再流 |
Effects of intracoronary administration of tirofiban in acute myocardial infarction patients with no reflow phenomenon after primary percutaneous coronary intervention |
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| ZHU Qiang,LIU Fuyuan,LI Xiaolan,ZHU Lei,LUO Feng,LI Xiaomei,LI Jing,LU Li.Effects of intracoronary administration of tirofiban in acute myocardial infarction patients with no reflow phenomenon after primary percutaneous coronary intervention[J].Journal of Clinical Cardiology,2011,27(1). |
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| Authors: | ZHU Qiang LIU Fuyuan LI Xiaolan ZHU Lei LUO Feng LI Xiaomei LI Jing LU Li |
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| Institution: | ZHU Qiang LIU Fuyuan LI Xiaolan ZHU Lei LUO Feng LI Xiaomei LI Jing LU Li(Hubei Provime Xiangfang No.1 Peaple's Hospital,Xiangfang,441000,China) |
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| Abstract: | |
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| Keywords: | tirofiban diltiazem ST-segment elevation myocardial infarction percutaneous coronary intervention no-reflow phenomenon |
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