Diet quality in association to lipidaemic profile in adults of families at high-risk for type 2 diabetes in Europe: The Feel4Diabetes study期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Diet quality in association to lipidaemic profile in adults of families at high-risk for type 2 diabetes in Europe: The Feel4Diabetes study

Institution:	1. Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece;2. Laboratory of Dietetics and Quality of Life, Department of Food Science & Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, Athens, Greece;3. Department of Paediatrics, Medical University Varna, Varna, Bulgaria;4. National and Kapodistrian University of Athens Medical School, 11527 Athens, Greece;5. Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria;6. Instituto Investigación Sanitaria Aragón (IISA), CIBERCV, Zaragoza, Spain;7. Unidad Clínica y de Investigación en Lípidos y Arteriosclerosis, Hospital Universitario Miguel Servet, Instituto de Investigación Sanitaria Aragón (IIS Aragón) CIBERCV, Zaragoza, Spain;8. University of Debrecen, Faculty of Health, Debrecen, Hungary;9. Hungarian Society of Nutrition, 1088 Budapest, Hungary;10. Division of Health Promotion, Department of Preventive Medicine, Faculty of Public Health, University of Debrecen, 4032 Debrecen, Hungary;11. Department of Public Health Solutions, Finnish Institute for Health and Welfare, Mannerheimintie 166, Helsinki, Finland;12. Department of Movement and Sports Sciences, Faculty of Medicine and Health Sciences, Ghent University, 9000 Gent, Belgium;13. Institute of Agri-food and Life Sciences, Hellenic Mediterranean University Research Centre, Agro-Health, Heraklion, Greece;1. Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia;2. Department of Kinesiology, University of Georgia, Athens, USA;3. The Nuffield Department of Women''s & Reproductive Health, University of Oxford, Oxford, UK;4. Murdoch Children''s Research Institute, Melbourne, Australia;5. Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia;6. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland;7. Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland;1. Department of Clinical Medicine and Surgery, ‘Federico II’ University of Naples, Naples, Italy;2. Department of Medicine and Surgery, University of Insubria, Varese, Italy and Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institutes, IRCCS Tradate, Varese, Italy;3. Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy;4. Department “Scuola Medica Salernitana”, Baronissi, SA, University of Salerno;5. Clinica Medica, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy;6. Department of Life, Health and Environmental Sciences, University of L''Aquila, L''Aquila, Italy;7. Studium Patavinum, Department of Medicine, University of Padua, Padua, Italy;8. Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy;9. Hypertension and Cardiovascular Risk Factors Research Center, Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy;10. Department of Public Health, “Federico II” University of Naples, Naples, Italy;11. Nephrology, Dialysis and Transplantation Unit, Department of Emergency and Organ Transplantation, “Aldo Moro” University of Bari, Bari, Italy;12. Cardiology IV, “A.De Gasperi''s” Department, Niguarda Ca’ Granda Hospital, Milan, Italy;13. School of Medicine and Surgery, Milano-Bicocca University, Milan, Italy;14. Department of Advanced Biomedical Sciences, “Federico II” University of Naples, Naples, Italy;15. Italian Society of General Medicine, Avezzano, L''Aquila, Italy;p. CNR-IFC, Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Cal Unit, Reggio Calabria, Italy;q. Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy;r. Department of Internal Medicine, Santa Maria Della Misericordia General Hospital, AULSS 5 Polesana, Rovigo, Italy;s. Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy;t. Department of Biomedical Science and Oncology, University of Bari, Bari, Italy;u. Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy;v. Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy;w. Department of Internal Medicine, University of Genoa and IRCCS Ospedale Policlinico San Martino, Genoa, Italy;x. Medicina Interna I, Ca’ Foncello University Hospital, Treviso, Italy;y. Department of Medicine and Centro di Ricerca Clinica e Traslazionale (CERICLET), University of Perugia, Perugia, Italy;z. Department of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence, Florence, Italy;11. Department of Medicine, University of Padua, Padua, Italy;12. Hypertension Unit, Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome Sapienza, Sant’Andrea Hospital, Rome, Italy;13. Hospital S. Maria Della Misericordia, Perugia, Italy;1. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People''s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China;2. Department of Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People''s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China;3. The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China;4. Department of Cardiology, The First People''s Hospital of Foshan, Guangdong Province, 528000, China;5. Guangdong Provincial People''s Hospital, School of Medicine, South China University of Technology, Guangzhou, 510100, China;6. Department of Cardiology, Longyan First Hospital Affiliated with Fujian Medical University, Longyan, 364000, China;7. Department of Information Technology, Guangdong Provincial People''s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China

Abstract:	Background and aimsThe role of diet in blood lipids is scarcely investigated in adults at risk of Type 2 Diabetes Mellitus (T2DM) and even less studied regarding their socioeconomic status (SES). This study aimed to investigate the associations of diet quality with blood lipids in adults from families at high-risk for developing T2DM from six European countries, considering their SES.Methods and resultsIn total 2049 adults (67% women) from relatively low-SES regions and high T2DM risk families were enrolled. Dietary habits, sedentary behaviour and sociodemographic characteristics were assessed using standardised questionnaires. The associations of tertiles of healthy diet score (HDS) with blood lipids were tested by univariate analysis of variance (UNIANOVA). HDL-Cholesterol (HDL-C) was positively (B 1.54 95%CI 0.08 to 2.99) and LDL-Cholesterol (LDL-C) (B ?4.15 95%CI ?7.82 to ?0.48), ratio of total cholesterol to HDL-C (B ?0.24 95%CI ?0.37 to ?0.10), ratio of LDL-C to HDL-C (B ?0.18 95%CI ?0.28 to ?0.08) and Atherogenic Index of Plasma (B ?0.03 95%CI ?0.06 to 0.00) inversely associated with the highest tertile of diet score compared to the lowest tertile independently of age, sex, Body Mass Index, total screen time and smoking. In sub-analysis of education (<14 and ≥ 14 years of education), these findings were only significant in the high-SES group.ConclusionWhile diet quality was poorer in the low-SES group, an association between diet quality and lipidemic profile was not found, as increased central obesity and smoking prevalence might have confounded this association. These findings indicate the need for tailor-made interventions, guided by the specific risk factors identified per population sub groups.

Keywords:	Lipids Cholesterol Diet Education Diabetes CVD"} {"#name":"keyword" "$":{"id":"kwrd0040"} "$$":[{"#name":"text" "_":"Cardiovascular Disease T2DM"} {"#name":"keyword" "$":{"id":"kwrd0050"} "$$":[{"#name":"text" "_":"Type 2 Diabetes Mellitus HDL-C"} {"#name":"keyword" "$":{"id":"kwrd0060"} "$$":[{"#name":"text" "_":"High-Density Lipoprotein Cholesterol AHEI"} {"#name":"keyword" "$":{"id":"kwrd0070"} "$$":[{"#name":"text" "_":"Alternate Healthy Eating Index MDS"} {"#name":"keyword" "$":{"id":"kwrd0080"} "$$":[{"#name":"text" "_":"Mediterranean Diet Score DQI"} {"#name":"keyword" "$":{"id":"kwrd0090"} "$$":[{"#name":"text" "_":"Diet Quality Index LDL-C"} {"#name":"keyword" "$":{"id":"kwrd0100"} "$$":[{"#name":"text" "_":"Low-Density Lipoprotein Cholesterol TC"} {"#name":"keyword" "$":{"id":"kwrd0110"} "$$":[{"#name":"text" "_":"Total Cholesterol TG"} {"#name":"keyword" "$":{"id":"kwrd0120"} "$$":[{"#name":"text" "_":"Triglycerides SES"} {"#name":"keyword" "$":{"id":"kwrd0130"} "$$":[{"#name":"text" "_":"Socioeconomic Status FINDRISC"} {"#name":"keyword" "$":{"id":"kwrd0140"} "$$":[{"#name":"text" "_":"Finnish Diabetes Risk Score BMI"} {"#name":"keyword" "$":{"id":"kwrd0150"} "$$":[{"#name":"text" "_":"Body Mass Index WHO"} {"#name":"keyword" "$":{"id":"kwrd0160"} "$$":[{"#name":"text" "_":"World Health Organization WC"} {"#name":"keyword" "$":{"id":"kwrd0170"} "$$":[{"#name":"text" "_":"Waist Circumference BP"} {"#name":"keyword" "$":{"id":"kwrd0180"} "$$":[{"#name":"text" "_":"Blood Pressure IFG"} {"#name":"keyword" "$":{"id":"kwrd0190"} "$$":[{"#name":"text" "_":"Impaired Fasting Glucose IGT"} {"#name":"keyword" "$":{"id":"kwrd0200"} "$$":[{"#name":"text" "_":"Impaired Glucose Tolerance OGTT"} {"#name":"keyword" "$":{"id":"kwrd0210"} "$$":[{"#name":"text" "_":"Oral Glucose Tolerance Test NCEP"} {"#name":"keyword" "$":{"id":"kwrd0220"} "$$":[{"#name":"text" "_":"National Cholesterol Education Program AIP"} {"#name":"keyword" "$":{"id":"kwrd0230"} "$$":[{"#name":"text" "_":"Atherogenic Index of Plasma HDS"} {"#name":"keyword" "$":{"id":"kwrd0240"} "$$":[{"#name":"text" "_":"Healthy Diet Score UNIANOVA"} {"#name":"keyword" "$":{"id":"kwrd0250"} "$$":[{"#name":"text" "_":"Univariate Analysis of Variance
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