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Trends of self-reported non-adherence among type 2 diabetes medication users in the United States across three years using the self-reported Medication Adherence Reasons Scale
Institution:1. Touro College of Pharmacy, 230 West 125th Street, New York, NY 10027, USA;2. Kantar Health, 51 Valley Stream Pkwy, Malvern, PA 19355, USA;1. Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Science, Tehran, Iran;2. Imaging Department, Taleghani Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran;3. Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Science, Tehran, Iran;4. Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Science, Tehran, Iran;1. School of Public Health, Medical College of Soochow University, Suzhou, China;2. Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China;1. Cardiovascular Prevention & Research Unit, Clinic & Laboratory of Pathophysiology, Department of Medicine, National and Kapodistrian University of Athens, Greece;2. Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Greece;3. Department of Food Science and Human Nutrition, Agricultural University of Athens, Greece;4. Hellenic Foundation for Cardiovascular Health and Nutrition, Athens, Greece;5. 1st Department of Propaedeutic and Internal Medicine & Joint Rheumatology Program, National and Kapodistrian University of Athens, Medical School, Greece;1. Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China;2. Institute of Food Safety and Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China;1. Department of Community Medicine, ESIC Medical College and PGIMSR, K.K. Nagar, Chennai, India;2. Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India;3. Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India
Abstract:Background & aimsTo determine the trends of self-reported non-adherence rates among adults taking Type 2 medicines (T2D) medicines between 2017 and 2019 and to identify the patterns for the frequently reported reasons for non-adherence in the United States.Methods & resultsData from the National Health and Wellness Survey, a self-administered, internet-based cross-sectional survey of US adults from 2017 to 2019 was used. Non-adherence was measured using the self-reported Medication Adherence Reasons Scale (MAR-Scale). Frequencies were used to identify the reasons for non-adherence for insulin and non-insulin therapies for T2D.Data were obtained from 2983 respondents in 2017, 5416 in 2018, and 5268 in 2019. Based on the MAR-Scale, the self-reported medication non-adherence rate was 25% in 2017, 21% in 2018, and 27% in 2019. The most common reason for non-adherence across all the three years was simple forgetfulness, yet patients reported the lowest mean number of days missing medication for that reason. Though less frequently reported, non-adherence lasted longer when patient did not know how to take their medicines, cost was a reason, or had concerns about the long term effects of the medicines.ConclusionsWith no significant improvement in adherence with T2D medicines over time, regardless of better awareness and extensive diabetes education, focus should be on individualized non-adherence reasons-based interventions.
Keywords:Medication adherence  Type 2 diabetes medicines  Medication Adherence Reasons Scale  Trend over time  Reasons for non-adherence  National Health and Wellness Survey
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