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Treat-to-target strategy in patients with rheumatoid arthritis: Audit of adherence from real world clinical data
Authors:José-Luis Andréu  María Auxiliadora Martín  Héctor Corominas  José Javier Pérez-Venegas  José Andrés Román-Ivorra  Fernando Sánchez-Alonso  Ángel Gil de Miguel
Institution:1. Rheumatology Department, H.U. Puerta de Hierro Majadahonda, Majadahonda, Spain;2. Research Unit, Sociedad Española de Reumatología, Madrid, Spain;3. Unitat territorial de Reumatologia, Hospital Universitari de Sant Pau & Hospital Dos de Maig, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain;4. Rheumatology Department, H.C.U. Virgen Macarena, Sevilla, Spain;5. Rheumatology Department, H.U.P. La Fe, Valencia, Spain;6. Cátedra de Medicina Preventiva y Salud Pública, Universidad Rey Juan Carlos, Madrid, Spain
Abstract:IntroductionThe current paradigm of the management of rheumatoid arthritis (RA) recommends achieving a state of remission or low disease activity through the treat-to-target strategy. Our study assesses adherence to this strategy.MethodPatients with RA (ACR-EULAR 2010 criteria) were included. From each centre, 19 patients were randomly selected. Clinical histories (CH) were assessed by independent auditors, checking compliance with predefined quality criteria. The study was approved by ethics committees.ResultsWe included 856 patients (mean age 54 years; 71% women). The use of a combined index (CI) was recorded in 61% of cases. Visits were recorded every 4 weeks using a CI in 4% of CH while attempts were made to achieve remission. Monitoring of disease activity every 6–8 months after reaching the target was recorded in 73% of cases.ConclusionsThe implementation of the treat-to-target strategy is barely recorded in patients with RA in routine clinical practice.
Keywords:Rheumatoid arthritis  Treat-to-target  Artritis reumatoide  Terapia por objetivos
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