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老年心力衰竭患者血浆脑钠素含量与心功能的关系
引用本文:苗磊,毛文珍.老年心力衰竭患者血浆脑钠素含量与心功能的关系[J].心血管康复医学杂志,2007,16(2):151-152.
作者姓名:苗磊  毛文珍
作者单位:辽宁省金秋医院心内科,辽宁,沈阳市,110015
摘    要:目的:探讨老年心力衰竭患者血浆脑纳素(BNP)水平与心力衰竭严重程度,左室功能的关系。方法:采用免疫荧光法测定63例心力衰竭患者和30例对照组血浆BNP浓度,用心脏彩色多普勒超声诊断仪测定并比较各组左室射血分数(LVEF)。结果:心力衰竭患者BNP浓度显著高于对照组(P<0.01);BNP水平随着心功能NY-HA分级程度的加重而显著增高,其与LVEF呈负相关(r=-0.58,P<0.001)。结论:老年心力衰竭患者血浆BNP水平随着心力衰竭严重程度的增加而升高,可反映左室功能状态。

关 键 词:老年人  心力衰竭  充血性  脑钠素
文章编号:1008-0074(2007)02-0151-02
收稿时间:2006-10-24
修稿时间:2006年10月24

Correlation between the serum brain natriuretic peptide levels and left ventricular function in aged patients with heart failure
MIAO Lei,MAO Wen-zhen.Correlation between the serum brain natriuretic peptide levels and left ventricular function in aged patients with heart failure[J].Chinese Journal of Cardiovascular Rehabilitation Medicine,2007,16(2):151-152.
Authors:MIAO Lei  MAO Wen-zhen
Abstract:Objective:To investigate the correlation among the blood plasma brain natriuretic peptide(BNP)levels and the severity of heart failure(HF)as well as left ventricular function in aged patients with heart failure.Methods:A total of 63 patients with HF and 30 control subjects were investigated by measuring the serum BNP levels and the left ventricular ejection fraction(LVEF).Results:The blood plasma BNP levels in patients with HF were markedly higher than those of control subjects(P<0.01),and the increase of BNP levels was closely correlated with the severity of NYHA functional class.The BNP levels were correlated negatively with the LVEF(r=-0.58,P<0.001).Conclusion:The BNP level is closely correlated with the severity of HF in aged patients with heart failure.
Keywords:The aged  Heart failure  congestive  Brain natriuretic peptide
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