PS结合CPAP治疗新生儿肺透明膜病的疗效

目的 探讨PS(肺表面活性物质)结合CPAP(鼻塞式持续气道正压通气)对新生儿肺透明膜病患儿的治疗效果.方法 随机选取医院2016年8月—2018年8月收治的106例新生儿肺透明膜病患儿,并将其均分为常规组(n=53)与联合组(n=53).其中对常规组患儿单纯用鼻塞式持续气道正压通气治疗,对联合组患儿在前者基础上配合肺表面活性物质治疗.结果 联合组患儿治愈率显著高于常规组,差异有统计学意义(P<0.05);与常规组患儿相比,联合组患儿肺炎发生率更低,且氧疗时间更短,差异有统计学意义(P<0.05).结论 肺表面活性物质联合鼻塞式持续气道正压通气治疗新生儿肺透明膜病,其疗效更明显,可在提高临床治愈率的同时,减少肺炎发生率并缩短氧疗时间.

Therapeutic Effect of PS Combined With CPAP on Hyaline Membrane Disease of Newborn

Objective To investigate the therapeutic effect of pulmonary surfactant combined with nasal obstruction continuous positive airway pressure(CPAP)on neonatal children with pulmonary hyaline membrane disease.Methods 106 neonatal patients with pulmonary hyaline membrane disease admitted to our hospital from August 2016 to August 2018 were randomly selected and divided into the conventional group(n=53)and the combined group(n=53).Among them,children in the conventional group were treated with nasal obstruction type continuous positive airway pressure ventilation alone,while children in the combined group were treated with pulmonary surfactant on the basis of the former.Results The cure rate in the combined group was significantly higher than that in the conventional group,and the difference was statistically significant(P<0.05).Compared with the conventional group,the incidence of pneumonia in the combined group was lower,and the duration of oxygen therapy was shorter,with statistically significant differences(P<0.05).Conclusion Pulmonary surfactant combined with nasal obstruction continuous positive airway pressure is more effective in the treatment of neonatal pulmonary hyaline membrane disease,which can improve the clinical cure rate,reduce the incidence of pneumonia and shorten the duration of oxygen therapy.