肝内胆汁淤积症孕妇的胎儿不良结局分析

目的对肝内胆汁淤积症孕妇的胎儿不良结局进行分析研究。方法随机选择在本院接受治疗的肝内胆汁淤积症孕妇作为观察组,与同期在本院正常分娩的对照组孕妇相比胎儿的不良结局。结果观察组的分娩结果 :12例早产、5例流产、5例死胎、4例新生儿窒息、40例正常分娩。对照组的分娩结果 :1例早产、1例新生儿窒息,64例正常分娩。观察组中胎儿不良结局发生率显著高于对照组,P <0.05;观察组中重度患者的胎儿不良结局发生率高于轻度患者,P <0.05。结论肝内胆汁淤积症导致胎儿不良结局发生率升高,应对加强对肝内胆汁淤积症的预防从而改善胎儿结局。

Analysis of Adverse Fetal Outcomes in Pregnant Women With Intrahepatic Cholestasis

Objective To analyze the adverse fetal outcomes of the pregnant women with intrahepatic cholestasis. Methods The pregnant women who received the treatment in our hospital were randomly selected as the observation group and compared with the pregnant women in the normal delivery in our hospital in the same period. Results The results of delivery in the observation group: 12 cases of premature delivery, 5 cases of abortion, 5 cases of stillbirth, 4 cases of neonatal asphyxia, 40 cases of normal delivery. The results of delivery in the control group: 1 case of premature delivery, 1 case of neonatal asphyxia, 64 cases of normal delivery. The incidence of fetal adverse outcome in the observation group was significantly higher than that in the control group(P < 0.05);the incidence of fetal adverse outcome in the observation group was higher than that in the mild group(P < 0.05). Conclusion Intrahepatic cholestasis leads to an increase in the incidence of fetal adverse outcomes. It is necessary to strengthen the prevention of intrahepatic cholestasis so as to improve the fetal outcome.