联合自—异体板层角膜移植减少排斥反应研究

目的观察联合自异体板层角膜移植术对植片免疫排斥反应的发生率及疗效。方法对２３例（２４只眼）已切除侵犯瞳孔区的翼状胬肉及中央板层角膜患者，分别在周边和中央行自异体植片移植术。另与单纯行胬肉或角膜皮样瘤切除、原位异体板层角膜移植术的１３例（１３只眼）患者进行对照，比较其排斥反应的发生率和疗效。结果自异体移植组的植片全部透明，无一例发生排斥反应和翼状胬肉复发。对照组则有３０．８％发生排斥反应，２０．０％翼状胬肉复发。结论联合自异体板层角膜移植术可减少排斥反应及翼状胬肉的复发

A clinical study on reducing immunologic rejection in combining corneal lamellar autografting with allografting

Objective To reduce the rate of immunologic rejection, corneal lamellar autografting with allografting were combined, making immune cells less attack on allograft. Methods The pterygium having encroached upon the pupillary area was removed surgically, and the combination of autograft with allograft was transplanted on the peripheral and central cornea in 23 cases (24 eyes). The control group of 13 cases (13 eyes) was established in which the pterygium and dermoids were removed, and lamellar allografts were transplanted. The rate of rejection and their effects were compared. Results The rate of transparent autograft and allograft was 100%, no rejection and recurrence of pterygium occurred in any case in the combined group, while in the control group, the rejection rate was 30.8% and recurrence rate, 20.0%. Conclusion The combination of lamellar autografting with allografting can reduce the rate of rejection and recurrence of pterygium.