重视翼状胬肉的基础与临床研究

翼状胬肉是我国常见、多发的眼表疾病，发病与复发机制仍不完全清楚，且缺乏手术与药物治疗的规范。翼状胬肉的主要诱因是环境刺激（紫外线），重要机制是角膜缘上皮屏障破坏，基本病理是结膜变性与增生。本文综合翼状胬肉发病机制的各种有关因素，以机制图显示并提出若干值得进一步商榷与深入研究的问题，推荐初次手术选择切除加自体结膜移植，或切除加羊膜移植，或带角膜缘上皮的自体结膜移植术式。临床上建议眼科医师重视翼状胬肉发病机制与临床诊治规范的研究，以减少此病的发病与复发。

Pay attention to basic and clinical research of pterygium

Pterygium is one of the most common ocular surface diseases. The pathogenesis of pterygium is unclear, and a guideline for drug therapy and surgical treatment has not been established up to now. Ultraviolet light is the most important etiologic factor of pterygium. Destruction of the limbal epithelium barrier is the most important mechanism of pterygium. The most important histopathogenesis of pterygium is degeneration and proliferation of conjunctiva. This article attempts to sketch the mechanism of pterygium and propose several questions for further investigation, and recommends excision of pterygium combined with conjunctival autograft or amniotic membrane graft or limbal conjunctival autograft as the primary surgical procedure. The study of the pathogenesis and clinical guideline for the diagnosis and treatment of pterygium should be emphasized in order to reduce the occurrence and recurrence of pterygium.