Adult-onset Coats disease |
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| Institution: | 1. Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the Netherlands;2. Department of Ophthalmology, Amsterdam University Medical Centers, Amsterdam, the Netherlands;3. Department of Human Genetics, Section Ophthalmogenetics, Amsterdam University Medical Centers, Amsterdam, the Netherlands;4. Queen Emma Center of Precision Medicine, Amsterdam University Medical Centers, Amsterdam, the Netherlands;5. Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands;6. Diagnostic Center for Complex Visual Disorders, Zeist, the Netherlands;1. International School of Public Health and One Health, Hainan Medical University, Haikou, China;2. Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun -Yat-sen University, Haikou, China;1. Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada;2. Department of Ophthalmology, St. Michael''s Hospital/Unity Health, Toronto, Ontario, Canada;3. Kensington Vision and Research Centre, Toronto, Ontario, Canada;4. Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle-Upon-Tyne, United Kingdom;5. Translational and Clinical Research Institute, Newcastle University, Newcastle-Upon-Tyne, United Kingdom;6. Cytokine and Imaging Laboratory, University of Toronto/Kensington Health Ophthalmology Biobank, Toronto, Ontario, Canada;1. Department of Ophthalmology, São Paulo Federal University, São Paulo, SP, Brazil;2. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA;3. University of the Philippines College of Medicine, Manila, Philippines;4. Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA;5. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA;6. Joslin Diabetes Center, Harvard Medical School, Beetham Eye Institute, Boston, MA, USA;7. Philippine Eye Research Institute, University of the Philippines, Manila, Philippines;8. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA;9. Vision Institute, Instituto Paulista de Estudos e Pesquisas em Oftalmologia (IPEPO), São Paulo, SP, Brazil |
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| Abstract: | Coats disease is an idiopathic retinal vasculopathy characterized by telangiectasia and aneurysm of retinal vessels along with intra and subretinal exudation and fluid. While Coats disease is classically described in young male population, there is an adult variant of Coats disease presenting in adulthood. Adult onset Coats disease have a similar presentation but a slower progression, localised lipid deposition, both peripheral and juxta-macular involvement. In this review article, we have attempted to describe in detail the characteristic clinical features, pathogenesis, investigation modalities and treatment in adult-onset Coats disease. |
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| Keywords: | Multimodal imaging Retinal vasculopathy |
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