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First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India |
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| Authors: | Kulandai Lily Therese Meena Lakshmipathy Dhanurekha Lakshmipathy |
| Institution: | L and T Microbiology Research Centre, Vision Research Foundation, Chennai, Tamil Nadu, India;1.C J Shah Cornea Services, Medical Research Foundation, Chennai, Tamil Nadu, India;2.Sankara Nethralya Referral Laboratory, Medical Research Foundation, Chennai, Tamil Nadu, India |
| Abstract: | A young 33 year old male presented with non-resolving corneal infiltrate for 2 month duration in the right eye. KOH/ Calcoflour wet mount revealed sparsely septate fungal hyphae. Post therapeutic penetrating keratoplasty 3 doses of intracameral voriconazole(100μg/0.1ml) was administered suspecting recurrence. Fungal culture revealed non sporulating mould on SDA. PCR based DNA sequencing targeting the ITS region identified the fungal isolate as Mortierella wolfii (M. wolfii) belonging to zygomycetes. To the best of our knowledge, this is the first report of human fungal keratitis caused by M. wolfii. |
| Keywords: | DNA sequencing fungal keratitis Mortierella wolfii non sporulating mould (NSM) therapeutic penetrating keratoplasty |