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Tissue factor with age-related macular degeneration
Authors:Guan-Feng Wang and Xiu-Lan Zou
Institution:Department of Ophthalmology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, Guangdong Province, China;Jinan University, Guangzhou 510630, Guangdong Province, China;Department of Ophthalmology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, Guangdong Province, China
Abstract:Wet age-related macular degeneration which incidence increases year by year is a blinding eye disease, but current clinical methods of treatment on this disease arelimited and the outcome is not ideal. Recent studies have found abnormally high expression of tissue factors which are targets for the treatment of wet age-related macular degeneration to achieve a certain effect in the choroidal neovascularization. Related literatures are reviewed as following.
Keywords:wet age-related macular degeneration  choroidal neovascularzation  tissue factor  photodynamic therapy  immunotherapy
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