不同人工泪液缓解白内障超声乳化术后干眼症状的效果

目的：探究聚乙二醇滴眼液、聚丙烯酸眼胶及玻璃酸钠滴眼液缓解白内障超声乳化术后干眼症状的效果。

方法：选择2015-02/2018-01于我院行白内障超声乳化术联合人工晶状体植入的年龄相关性白内障患者纳入研究，根据使用人工泪液种类的不同将患者分为聚乙二醇组、聚丙烯酸组及玻璃酸钠组。观察并分析三组患者术后7、14、30d时临床症状评分、Schirmer I试验、泪膜破裂时间(BUT)、角膜荧光素染色情况。

结果：术后14、30d时玻璃酸钠组干眼症状评分、Schirmer Ⅰ情况及BUT显著优于聚乙二醇组及聚丙烯酸组(P<0.05)； 术后30d时玻璃酸钠组患者染色评分及泪膜成像评分显著低于其他两组(P<0.05)； 聚乙二醇组及聚丙烯酸组各指标组间比较差异无统计学意义(P>0.05)。

结论：聚乙二醇滴眼液、聚丙烯酸眼胶及玻璃酸钠滴眼液均可缓解白内障术后干眼临床症状，改善泪膜状态，具有较好的临床疗效，其中玻璃酸钠滴眼液可能更具优势。

Effect of different artificial tears on relieving dry eye symptoms after phacoemulsification of cataract

AIM: To investigate the curative effect of polyethylene glycol(PEG)eye drops, polyacrylic acid(PAA)eye gel and sodium hyaluronate(SH)eye drops on dry eye syndrome after phacoemulsification.

METHODS: Patients with age-related cataract who underwent phacoemulsification and intraocular lens implantation in the hospital from February 2015 to January 2018 were enrolled in the study. They were divided into PEG group, PAA group and SH group according to the application type of artificial tears. The clinical symptom scores, Schirmer I test, break-up time(BUT)and corneal fluorescein staining were observed and analyzed at 7, 14 and 30d after operation in the three groups. The curative effects were evaluated.

RESULTS: After 14 and 30d of operation, the score of dry eye symptom, Schirmer I and BUT in SH group were significantly better than those in PEG group and PAA group(P<0.05). The staining score and tear film imaging score in SH group were significantly lower than those in the other two groups at 30 days after operation(P<0.05). There was no significant difference in all indexes between PEG group and PAA group(P>0.05).

CONCLUSION: PEG drops, PAA eye gel and SH eye drops all can alleviate the clinical symptoms of dry eye patients after cataract surgery, improve the state of tear film, which have good clinical curative effects. SH eye drops may be more advantageous.