中心性浆液性脉络膜视网膜病变治疗方法的研究进展

中心性浆液性脉络膜视网膜病变( central serous chorioretinopathy,CSC)是中心视力损失的一项重要原因,它主要好发于中青年男性,以后极部浆液性神经上皮层脱离伴有视网膜色素上皮( retinal pigment epithelium,RPE)水平的渗漏为特征。大多数急性CSC患者会自发吸收,但是对于持续性神经上皮层脱离的慢性CSC患者可能会发展为进展性的视力下降。本文对近年来关于CSC治疗方法的研究进展作简要综述,主要从激光光凝、光动力学疗法( PDT)、玻璃体内抗血管内皮生长因子治疗、醛固酮受体拮抗剂四方面进行阐述。

Progress in the treatment of central serous chorioretinopathy

Central serous chorioretinopathy(CSC)is an important cause for central vision loss. It mostly occurs in young and middle-aged men. It is a condition characterized by a serous detachment of neurosensory retina at the posterior pole and leakage from the retinal pigment epithelium(RPE). Most patients with acute CSC will resolve spontaneously. However, in cases of chronic CSC with persistent serous retinal detachment, patients might develop progressive vision loss. This article was made a brief review of the current treatment methods, including laser, photodynamic therapy(PDT), intravitreal anti-vascular endothelial growth factor therapy and the mineralocorticoid receptor antagonists.