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房水流出通路结构及功能显像的研究进展
引用本文:李雅頔,陈燕华,孙子雯,李楠钰,胡竹林.房水流出通路结构及功能显像的研究进展[J].国际眼科杂志,2021,21(7):1196-1199.
作者姓名:李雅頔  陈燕华  孙子雯  李楠钰  胡竹林
作者单位:中国云南省昆明市,昆明医科大学第四附属医院眼科 云南省第二人民医院眼科 云南省眼科研究所 云南省眼部疾病临床医学研究中心 云南省眼病临床医学中心 云南省眼科疾病防治研究重点实验室 云南省第二人民医院白内障与眼底疾病防治省创新团队 云南省姚克专家工作站,中国云南省昆明市,昆明医科大学第四附属医院眼科 云南省第二人民医院眼科 云南省眼科研究所 云南省眼部疾病临床医学研究中心 云南省眼病临床医学中心 云南省眼科疾病防治研究重点实验室 云南省第二人民医院白内障与眼底疾病防治省创新团队 云南省姚克专家工作站,中国云南省昆明市,昆明医科大学第四附属医院眼科 云南省第二人民医院眼科 云南省眼科研究所 云南省眼部疾病临床医学研究中心 云南省眼病临床医学中心 云南省眼科疾病防治研究重点实验室 云南省第二人民医院白内障与眼底疾病防治省创新团队 云南省姚克专家工作站,中国云南省昆明市,昆明医科大学第四附属医院眼科 云南省第二人民医院眼科 云南省眼科研究所 云南省眼部疾病临床医学研究中心 云南省眼病临床医学中心 云南省眼科疾病防治研究重点实验室 云南省第二人民医院白内障与眼底疾病防治省创新团队 云南省姚克专家工作站,中国云南省昆明市,昆明医科大学第四附属医院眼科 云南省第二人民医院眼科 云南省眼科研究所 云南省眼部疾病临床医学研究中心 云南省眼病临床医学中心 云南省眼科疾病防治研究重点实验室 云南省第二人民医院白内障与眼底疾病防治省创新团队 云南省姚克专家工作站
基金项目:云南省创新团队计划任务(No.2017HC010); 云南省科技计划项目重大科技专项(No.2018ZF009)
摘    要:

房水作为重要眼内容物之一,一直处于动态循环中,若房水流出通路(AHO)中的任一部位受阻,都将导致眼压升高,并伴随青光眼的发生,进而出现视神经损伤,严重影响视功能。而开角型青光眼患者的房角呈开放状态,其眼压升高是房水流出阻力增加所致,因此,直观地观察AHO的结构,评价其功能变化,有助于我们更清晰地了解AHO的阻力所在,进一步阐明开角型青光眼的发病机制。目前对于AHO的显像技术包括光学相干断层扫描(OCT)以及AHO造影术等。本文将就AHO结构及功能显像的研究进展做一综述。

关 键 词:房水流出通路    显像    光学相干断层扫描    造影术
修稿时间:2021/5/27 0:00:00

Advances in the structure and function imaging of aqueous humor outflow
Ya-Di Li,Yan-Hua Chen,Zi-Wen Sun,Nan-Yu Li and Zhu-Lin Hu.Advances in the structure and function imaging of aqueous humor outflow[J].International Journal of Ophthalmology,2021,21(7):1196-1199.
Authors:Ya-Di Li  Yan-Hua Chen  Zi-Wen Sun  Nan-Yu Li and Zhu-Lin Hu
Institution:Department of Ophthalmology,Fourth Affiliated Hospital of Kunming Medical University;Department of Ophthalmology, the Second People''s Hospital of Yunnan Province;Yunnan Eye Institute;the Ocular Disease and Clinical Medicine Research Center of Yunnan Province;the Ocular Disease Clinical Medicine Center of Yunnan Province;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology;Provincial Innovation Team for Cataract and Ocular Fundus Disease, the Second People''s Hospital of Yunnan Province;Expert Workstation of Yao Ke, Kunming 650000, Yunnan Province, China,Department of Ophthalmology,Fourth Affiliated Hospital of Kunming Medical University;Department of Ophthalmology, the Second People''s Hospital of Yunnan Province;Yunnan Eye Institute;the Ocular Disease and Clinical Medicine Research Center of Yunnan Province;the Ocular Disease Clinical Medicine Center of Yunnan Province;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology;Provincial Innovation Team for Cataract and Ocular Fundus Disease, the Second People''s Hospital of Yunnan Province;Expert Workstation of Yao Ke, Kunming 650000, Yunnan Province, China,Department of Ophthalmology,Fourth Affiliated Hospital of Kunming Medical University;Department of Ophthalmology, the Second People''s Hospital of Yunnan Province;Yunnan Eye Institute;the Ocular Disease and Clinical Medicine Research Center of Yunnan Province;the Ocular Disease Clinical Medicine Center of Yunnan Province;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology;Provincial Innovation Team for Cataract and Ocular Fundus Disease, the Second People''s Hospital of Yunnan Province;Expert Workstation of Yao Ke, Kunming 650000, Yunnan Province, China,Department of Ophthalmology,Fourth Affiliated Hospital of Kunming Medical University;Department of Ophthalmology, the Second People''s Hospital of Yunnan Province;Yunnan Eye Institute;the Ocular Disease and Clinical Medicine Research Center of Yunnan Province;the Ocular Disease Clinical Medicine Center of Yunnan Province;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology;Provincial Innovation Team for Cataract and Ocular Fundus Disease, the Second People''s Hospital of Yunnan Province;Expert Workstation of Yao Ke, Kunming 650000, Yunnan Province, China and Department of Ophthalmology,Fourth Affiliated Hospital of Kunming Medical University;Department of Ophthalmology, the Second People''s Hospital of Yunnan Province;Yunnan Eye Institute;the Ocular Disease and Clinical Medicine Research Center of Yunnan Province;the Ocular Disease Clinical Medicine Center of Yunnan Province;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology;Provincial Innovation Team for Cataract and Ocular Fundus Disease, the Second People''s Hospital of Yunnan Province;Expert Workstation of Yao Ke, Kunming 650000, Yunnan Province, China
Abstract:As one of the important contents of eyes, aqueous humor is always in dynamic circulation. When any part of the outflow is blocked, the aqueous humor outflow(AHO)circulation will break down, and followed by the increase of intraocular pressure, the damaged visual function, and the optic nerve injury. At last, the glaucoma occurs. Therefore, it can promote to locate the blocked part by observing the structure of the AHO and evaluating its function state, so as to clarify the pathogenesis of primary open angle glaucoma. Current imaging techniques for AHO pathway include optical coherence tomography(OCT)and angiography of outflow. This article will review the research progress of structure and function imaging of AHO.
Keywords:aqueous humor outflow  imaging  optical coherence tomography  angiography
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