玻璃体切割联合内界膜翻转术与传统内界膜剥离术治疗黄斑裂孔的疗效对比

目的探讨玻璃体切割联合内界膜翻转术与传统内界膜剥离术治疗特发性黄斑裂孔的形态学及功能学改变。方法对我院就诊的42例42眼黄斑裂孔患者进行研究,根据患者接受的手术方式不同将患者分为两组,组1患者接受玻璃体切割联合内界膜翻转术治疗,组2患者接受玻璃体切割联合传统内界膜撕除术。所有患者在治疗前及治疗后1个月、3个月,均完善裂隙灯下眼前段检查、非接触眼压测量、裂隙灯下眼底检查、最佳矫正视力测量、黄斑OCT检查,并将两组患者治疗前与治疗后1个月、3个月情况进行对比。结果两组患者治疗前年龄、性别、最佳矫正视力、眼别比例、非接触眼压、黄斑裂孔分期、黄斑裂孔直径、眼轴长度差异均无统计学意义(均为P>0.05)。组1治疗特发性黄斑裂孔封闭率(100.00%)高于组2(90.91%),差异无统计学意义(P>0.05)。两组患者术后1个月(P_组1<0.01,P_组2=0.03)、3个月(P_组1<0.01,P_组2<0.01)最佳矫正视力均较术前提高,差异均有统计学意义。两组患者术后1个月、3个月...

Efficacy analysis on vitrectomy combined with internal limiting membrane flap inversion comparing with vitrectomy combined with conventional internal limiting membrane peeling for treatment of macular hole

Objective To explore morphological and functional changes of idiopathic macular holes(IMH)treated by vitrectomy combined with internal limiting membrane(ILM)flap inversion or by conventional ILM peeling.Methods Forty-two IMH patients(42 eyes)visited our hospital were included.Patients were randomly divided into two groups according to the accepted operation modes.Patients in group I were treated with vitrectomy and ILM flap inversion,and those in group II were treated with vitrectomy and traditional ILM peeling.Anterior segment examination under slip lamp,non-contact IOP measurement,fundus examination under slip lamp,best correct visual acuity(BCVA)test,macular optical coherence tomography(OCT)were performed before the surgery and 1 month,3 months after the surgery.Patients’conditions 1 month,3 months after the surgery were compared with those before surgery.Results There was no significant different between two groups before surgery in age,sex,BCVA,ratio of eye side,non-contact IOP,stage of macular holes,diameter of macular hole or axial length(all P>0.05).Macular hole closure rate in group I(100.00%)was higher than that in group II(90.91%),and no difference was observed(P>0.05).BCVA got improvement 1 month and 3 months after surgery in both two groups comparing with those before surgery,and statistical difference was found(1 month after surgery Pgroup 1<0.01,Pgroup 2=0.03;3 months after surgery Pgroup 1<0.01,Pgroup 2=0.01).No difference was observed in BCVA by intra-group comparison 1 month and 3 months after surgery(all P>0.05).No difference was found in BCVA by inter-group comparison 1 month and 3 months after surgery(both P>0.05).Conclusion Vitrectomy combined with ILM flap inversion is an effective method for treatment of idiopathic macular hole,and it can get higher rate of anatomical closure than traditional ILM peeling,especially get higher operative successful rate in patients with longer axial length(axial length>28 mm).