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What should we tell parents? Congenital diaphragmatic hernia |
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| Authors: | Francesca M Russo Anne Debeer Paolo De Coppi Koenraad Devriendt Neeltje Crombag Talia Hubble Beverley Power Alexandra Benachi Jan Deprest |
| Institution: | 1. Clinical Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium;2. Academic Department of Development and Regeneration, Cluster Woman and Child, KU Leuven, Leuven, Belgium;3. Neonatal and Paediatric Surgery Unit, Great Ormond Street Hospital, London, UK;4. Center for Human Genetics, University Hospitals Leuven, Leuven, Belgium;5. CDH UK, King's Lynn, UK;6. Department of Obstetrics and Gynecology, Hôpital Antoine Béclère, AP-HP, Université Paris Saclay, Clamart, France |
| Abstract: | Congenital diaphragmatic hernia (CDH) is characterized by a defect in the muscle dividing the thoracic and abdominal cavities. This leads to herniation of the abdominal organs into the thorax and a disturbance of lung development. Two-thirds of cases are identified by prenatal ultrasound in the second trimester, which should prompt referral to a tertiary center for prognosis assessment and counseling by a multidisciplinary team familiar with this condition. In this review, we summarize evidence on prenatal diagnosis and postnatal management of CDH. There is a focus on information that should be provided to expecting parents during prenatal counseling. |
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