阴道超声照射对子宫内绒毛的影响

目的 了解经阴道超声照射对早期妊娠（早孕）妇胚胎的安全性。方法 将８０例欲终止妊娠的早孕妇女分为４组（各２０例）：Ⅰ组对照，不予超声照身；Ⅱ组经腹超声照射妊娠囊１０ｍｉｎ；Ⅲ组经阴道超声照射妊娠囊３ｍｉｎ；Ⅳ组经阴道超声照射妊娠囊１０ｍｉｎ。１ｈ后行人工流产术，取绒毛组织行电子显微镜超微结构观察，丙二醛（ＭＤＡ）、超氧化物歧化酶（ＳＯＤ）测定及姐妹染色单体交换率（ＳＣＥ）分析。结果 Ⅳ组绒毛断裂、

Influence of Sonographic Examination on Embryo Villi during Early Pregnancy

OBJECTIVE: To evaluate the effects of sonographic examination on embryo villi during early pregnancy. METHODS: Eighty early pregnant women intended for artificial abortion were divided into 4 groups: group I served as control, the remaining 3 groups underwent pelvic sonographic examination transabdominally for 10 minutes (group II), transvaginally for 3 minutes (group III) or for 10 minutes (group IV) respectively. After 1 hour embryo villi were obtained through artificial abortion and examined by electronic microscopy, biochemical methods and sister chromatid exchanges (SCE). RESULTS: In group IV, but not group II, III, the embryo microvilli were found broken, lost and disarranged. The rough endoplasmic reticulum of trophoblasts expanded. Their malondial dehyde levels increased while the superoxide dismutase (SOD) decreased as compared with control (P < 0.01). There was no difference of SCE among these 4 groups. CONCLUSION: It is recommended that sonographic examination should be done through abdominal approach for shorter than 10 minutes during early stage of pregnancy.