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放置TCu220c宫内节育器15年左右子宫内膜形态学的研究
引用本文:孙敬霞,韩燕燕,韩向阳,赵爽,韩旭,郑建华.放置TCu220c宫内节育器15年左右子宫内膜形态学的研究[J].中国实用妇科与产科杂志,2002,18(1):33-35.
作者姓名:孙敬霞  韩燕燕  韩向阳  赵爽  韩旭  郑建华
作者单位:1. 哈尔滨医科大学第一临床医学院妇产科,150001
2. 哈尔滨医科大学计划生育研究所
基金项目:国家计划生育委员会九五攻关资助课题 (课题号 :96 38)
摘    要:目的:探讨国产TCu220c宫内节育器(IUD)放置15年左右(13-17年)子宫内膜的形态学改变及其安全性,并为临床放置年限提供科学依据。方法:采用光镜、透射电镜,从组织病理学和超微结构病理学角度,对24例放置国产TCu220cIUD15年左右妇女的子宫内膜进行形态学研究。结果:TCu220cIUD放置15年左右,铜离子的作用在逐渐减弱,对子宫内膜的影响也在逐渐减轻,但TCu220cIUD仍然具有抗生育作用。子宫内 膜没有癌变倾向。对进入更年期的妇女,放置TCu220cIUD15年左右,子宫内膜仍无间变和癌变。结论:TCu220cIUD放置15年左右是较为安全的。

关 键 词:TCu220c宫内节育器  子宫内膜  电子显微镜  避孕工具
文章编号:1005-2216(2002)01-0033-03

Study on uterine endometrial morphology after TCu220c intrauterine device used for 15 years
Sun Jingxia ,Han Yanyan,Han Xiangyang,et al..Study on uterine endometrial morphology after TCu220c intrauterine device used for 15 years[J].Chinese Journal of Practical Gynecology and Obstetrics,2002,18(1):33-35.
Authors:Sun Jingxia  Han Yanyan  Han Xiangyang  
Institution:Sun Jingxia *,Han Yanyan,Han Xiangyang,et al. *Department of Obstetrics and Gynecology,the First Affiliated Hospital of Harbin Medical University Harbin 150001,China
Abstract:Objective We investigate the morphological changes of the endometrium after 15years' usage of TCu220c intrauterine device(IUD)in order to evaluate the safety of TCu220cIUD and provide scientific foundation for its usage duration.Methods Microscopy and transmission electromicroscopy were employed to investigate the endometrial morphology in 24 cases with 15years' usage of TCu220cIUD from the aspect of histopathology and ultra-structural pathology.Results After 15years' usage of TCu220cIUD,its effect on the uterine endometrium became less obvious.The effect of Cu 2 ion was reducing,yet the anti-fertility effect remained.There were no tendency of becoming carcinomatous.For those perimenopausal women,there was no endometrial atypical proliferation and carcinomatous change.Conclusion It is safe to use TCu220cIUD for about 15 years.
Keywords:TCu220cIUD  Uterine endometrium  Electromicroscope
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