卵泡穿刺配合人工授精治疗多囊卵巢综合征引起的不孕症

目的 了解阴道超声引导下卵泡穿刺后行人工授精治疗多囊卵巢综合征(polycysfic ovary syndrome，PCOS)所致不孕症的效果。方法 选择对克罗米芬治疗无反应的PCOS患者应用促排卵药治疗后，随机选择60例在阴道超声引导下卵泡穿刺后行人工授精术；另选择60例患者直接指导性生活。结果 对照组60例患者临床妊娠率23．33％，卵巢过度刺激综合征(ovarian hyperstimulation syndrome，OHSS)发生率40．00％，卵泡穿刺组60例患者临床妊娠率48．33％，OHSS发生率35．00％。结论 促排卵治疗后，阴道超声引导下卵泡穿刺配合人工授精治疗，提高了PCOS所致的不孕症患者的临床妊娠率，OHSS的发生率未降低。

Treatment of infertility of polycystic ovary syndrome by follicular puncture and intrauterus insemination

Objective To assess the effect of follicular puncture(FP) followed by intrauterus insemination(IUI)on infertility resulting from polycystic ovary syndrome (PCOS).Methods One hundred and twenty women with clomiphene citrate resistant PCOS were randomly divided into two groups.Experimental group(n=60)were treated by transvaginal ultrasound-guided FP and followed by IUI,and the control group(n=60)were instructed to have intercourse at home.Results The clinical pregnancy rate and the incidence of ovarian hyperstimulation syndrome(OHSS)were 23 33% and 40 00% respectively in control group,48 33% and 35 00% in experimental group.Conclusions The pregnancy rate of infertility of PCOS can be improved by controlled ovarian hyperstimulation,FP and followed by IUI.The incidence of OHSS is not affected.