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彩色多普勒超声监测子宫内膜和内膜下血流对IVF患者子宫容受性的预测价值
引用本文:高敏芝,李文英,刘桂梅,贾晓峰,张慧琴.彩色多普勒超声监测子宫内膜和内膜下血流对IVF患者子宫容受性的预测价值[J].生殖与避孕,2007,27(6):399-403.
作者姓名:高敏芝  李文英  刘桂梅  贾晓峰  张慧琴
作者单位:上海市计划生育科学研究所附属博康生殖医学医院,上海,200032
摘    要:目的:评价彩色多普勒超声监测子宫内膜和内膜下血流在IVF-ET中对子宫内膜容受性的预测价值。方法:选择第一次进行IVF/ICSI-ET治疗的不孕症患者119例,根据注射hCG日子宫内膜和内膜下血流状况分为A组(n=8):子宫内膜和内膜下血流≤2支;B组(n=50):子宫内膜和内膜下血流3-4支;C组(n=61):子宫内膜和内膜下血流≥5支。各组患者均移植1-3个胚胎。比较各组的临床特征、卵巢反应、内膜情况和妊娠结局。结果:各组的临床特征、卵巢反应、内膜情况均无统计学差异,A组妊娠率低于B组(P<0.05)和C组(P<0.01)。A组着床率低于C组(P<0.01),B组和C组的妊娠率和着床率均无明显差异(P>0.05)。结论:子宫内膜和内膜下血流在IVF-ET中对子宫内膜容受性有一定预测价值。IVF-ET周期中内膜和内膜下血流≤2支者建议当月不做胚胎移植,可待血流改善后再行胚胎移植术。

关 键 词:内膜和内膜下血流  子宫内膜容受性  体外受精-胚胎移植(IVF-ET)  彩色多普勒超声
文章编号:0253-357X(2007)06-0399-05
修稿时间:2007-03-22

Assessment of Uterine Receptivity by Endometrial and Subendometrial Blood Flows Measured by Vaginal Color Doppler Ultrasound in Women Undergoing IVF Treatment
Min-zhi GAO,Wen-ying LI,Gui-mei LIU,Xiao-feng JIA,Hui-qin ZHANG.Assessment of Uterine Receptivity by Endometrial and Subendometrial Blood Flows Measured by Vaginal Color Doppler Ultrasound in Women Undergoing IVF Treatment[J].Reproduction and Contraception,2007,27(6):399-403.
Authors:Min-zhi GAO  Wen-ying LI  Gui-mei LIU  Xiao-feng JIA  Hui-qin ZHANG
Institution:Shanghai Bokang Reproductive Hospital of Shanghai Instituted of Planned Parenthood Research, Shanghai, 200032
Abstract:Objective: To evaluate endometrial and subendometrial blood flows measured by vaginal color Doppler ultrasound as a predicator of endometrial receptivity in women undergoing IVF treatment. Methods: A total of 119 infertile patients undergoing the first IVF/ICSI-ET cycle were divided into 3 groups according to a color Doppler ultrasound examination performed on the day of hCG injection. Group A(n=8), endometrial and subendometrial blood flows were less than 2 branches; group B(n=50), endometrial and subendometrial blood flows were between 3 and 4 branches; group C(n=61), endometrial and subendometrial blood flows were more than 5 branches. Patients were transferred 1-3 embryos each. Demographic data, ovarian responses, endometrial thickness, PI, RI and IVF result among groups were compared. Results: Demographic data, ovarian responses, endometrial thickness, PI and RI among groups had no significant difference. The pregnancy rate of group A was significantly lower than that of group B (P<0.05) and group C (P<0.01). The implantation rate of group A was significantly lower than that of group C (P<0.01). There was no significant difference of the rate of pregnancy and implantation between group B and group C (P>0.05). Conclusion: Endometrial and subendometrial blood flows measured by vaginal color Doppler ultrasound is a good predicator of pregnancy during IVF treatment. A good endometrial and subendometrial blood flows is benefit for the result of IVF.
Keywords:endometrial and subendometrial blood flows  endometrial receptivity  in vitro fertilization-embryo transfer(IVF-ET)  color Doppler ultrasound
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