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The role of predictive vaginal biomarkers in women with cervical cerclage |
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| Authors: | Tomi T Kanninen Giovanni Sisti Mariarosaria Di Tommaso Vincenzo Berghella |
| Institution: | 1. Department of Obstetrics and Gynecology, Jamaica Hospital Medical Center, New York, NY, USA;2. Department of Health Science, University of Florence, Florence, Italy;3. Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA |
| Abstract: | Cervical cerclage is currently one of the primary methods of treatment for cervical insufficiency (CI). Identifying methods in order to selectively apply cerclage may allow us to further limit unnecessary procedures. In this regard, a limited number of inflammatory and extracellular matrix biomarkers measurable non-invasively at the level of the cervix have been examined. In this review we summarize the current research on the use of cervical biomarkers in predicting cerclage failure and propose potential objectives for future research. |
| Keywords: | Cerclage biomarkers cervical insufficiency preterm delivery |