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Theobromine does not affect postprandial lipid metabolism and duodenal gene expression,but has unfavorable effects on postprandial glucose and insulin responses in humans |
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| Authors: | Lotte Smolders Ronald P Mensink Mark V Boekschoten Rogier JJ de Ridder Jogchum Plat |
| Institution: | 1. Department of Human Biology and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Center, Maastricht, P.O. Box 616, 6200 MD, The Netherlands;2. Nutrition, Metabolism and Genomics Group, Wageningen University, Wageningen, The Netherlands;3. Division of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, The Netherlands |
| Abstract: | |
| Keywords: | Theobromine Postprandial Lipid metabolism Glucose metabolism Microarray apoA-I apolipoprotein A-I apoB100 apolipoprotein B100 apoB48 apolipoprotein B48 CVD cardiovascular diseases CYP1A2 cytochrome P450 1A2 CYP2E1 cytochrome P450 2E1 dAUC decremental area under the curve DBP diastolic blood pressure FFA free fatty acid FFQ food frequency questionnaires GSEA gene set enrichment analysis HDL-C high-density lipoprotein cholesterol hsCRP high sensitivity c-reactive protein iAUC incremental area under the curve IPA ingenuity pathway analysis LDL-C low density lipoprotein cholesterol SBP systolic blood pressure TAG triacylglycerol |
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