支架相关卫生技术评估研究是否对中国卫生政策有影响：基于文献研究的结果

目的：了解国内外与支架相关的技术评估研究,初步探索研究结论与我国卫生政策之间的关联。方法：采用文献复习法,在CNKI和PubMed数据库中检索文献和指南,并在卫生部和北京、上海、广州三地的相关网站查找与支架相关的政策,据此分析文献结论和政策内容的契合程度。结果：支架相关中英文文献数量逐年增加。中文相关系统综述类文献较少,大多聚焦于安全性和有效性,缺乏对成本效果的研究。中华医学会颁布的指南对支架,尤其是药物洗脱支架的适应症做了相关的说明,与文献结论相一致。与支架相关的政策共有6项,可分为集中招标采购政策、价格管理政策和技术管理规范等三类。前两类政策与成本相关的技术评估研究之间可能存在一定联系;技术管理规范则没有相应的研究证据。结论：尽管中国目前的支架相关文献量不算小,但对成本这一重点问题仍缺乏研究。指南内容和文献结论基本一致,但其他政策相对缺乏循证依据。

Does stents related health technology assessment have an impact on health policies in China: Based on the literature review

Objective： This study aimed to examine the relationship between researches on stents and related policies in China. Methods： The study reviewed and compared published scientific articles and policy documents related to stents. We retrieved literature and guidelines from China National Knowledge Infrastructure （ CNKI） and PubMed databases using＂stent＂as the key word,and searched policy documents in websites of the Chinese Ministry of Health and related websites of Beijing,Shanghai and Guangzhou. Results： Numbers of stent related papers are increasing both in Chinese and English. The number of Chinese systematic reviews and meta-analysis is too small to draw a conclusion. These papers are mainly about safety and effectiveness,but lack of content about cost effectiveness. We also found six policy documents regarding tendering procurement,price management and technique management standard. The first two types of policies may have some connection with cost related articles; however,the third one has no connection with stent related articles. Conclusions： Although there are many studies on stents,there is still a lack of cost-related studies to address this important health policy aspect in China. The indication of stents, especially drug eluting stents （ DES） in guideline is consistent with the evidence from the technology evaluations. However,other policy documents were still lack of evidence.