我国基本药物循证遴选评价指标体系的构建

目的:建立我国基本药物循证遴选指标体系和量化方法。方法:(1)文献研究:通过文献学习建立初步指标体系,经专家论证后,对指标进行调整,构建最终指标体系;(2)层次分析法:通过专家调查法,由专家对指标所构成的判断矩阵进行两两打分,确定各指标的权重。结果:对一级指标作出调整,同时对二级指标进行细化,提高其可操作性,最终建立的指标体系中包括一级指标8个,二级指标18个。结论:本研究建立的评价指标体系可用于评价基本药物目录收录的药品,为我国遴选基本药物目录的专家提供遴选证据。

Construction of evaluation index system for evidence based selection of essential medicines in China

Objective:To establish an evaluation index system and quantitative method of evidence-based selection of essential medicines in China and use Analytical Hierarchy Process (AHP) to construct the weight of the index. Methods:Through the expert consultation method, the initial index system was established, after the experts argument on the matrix of every two points, adjust the indicators, build the final index system, and then through the AHP, by the experts to determine the weight of the indicators. Results:Based on the literature study and expert consultation, the evaluation index system and its weight of the selection criteria of the basic drug were established. There are 8 indexes in the first-level indicators and the weight distribution was from high to low, the efficacy, safety, clinical guideline recommendation, quality reliability, economy, ease of use, list included, and availability. The secondary indicators include 18 indexes. To improve the operability, the first level indicators are adjusted while the second level indicators are refined simultaneously. Conclusion:The index evaluation system determined by expert argumentation and analytic hierarchy process in this study can be used to evaluate the medicines listed in the essential drug list and provide evidence for selection of essential medicines in China. It has certain theoretical feasibility. The empirical research shows that the index also has practical operability and can be improved.