大丰区2006—2015年肺癌发病和死亡趋势分析

目的 掌握大丰区2006—2015年肺癌发病和死亡水平及其变化趋势。方法 搜集、整理大丰区2006—2015年肿瘤登记资料,计算肺癌的发病率和死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、年龄别发病率和死亡率、肺癌在全部恶性肿瘤中的构成及其顺位等指标。采用Joinpoint软件,计算肺癌发病、死亡中标率的平均年度变化百分比(AAPC)及其95%可信区间(95%CI)。结果 2006—2015年大丰区共新发肺癌病例4 209例,发病率为58.13/10万,占全部恶性肿瘤发病的18.80%,中标发病率为33.44/10万;同期因肺癌死亡3 848例,死亡率为53.15/10万,占全部恶性肿瘤死亡的22.69%,中标死亡率为30.17/10万;肺癌在恶性肿瘤发病和死亡顺位中均居第一位。男性人群的发病率、死亡率及其中标率均高于女性。10年间,除男性人群肺癌的中标死亡率显著下降外,大丰区肺癌的中标发病率和中标死亡率均无明显变化趋势(P值均>0.05)。结论 肺癌是大丰区人群发病和死亡第一位的恶性肿瘤,全人群的发病死亡水平无明显变化,应继续加强相关防治研究工作。

Trend analysis of incidence and death of lung cancer in Dafeng District, 2006-2015

Objective To grasp the incidence and mortality as well as their trends of lung cancer in Dafeng District from 2006 to 2015. Methods The tumor registration data of Dafeng District between 2006 and 2015 were collected and cleared up. The incidence and mortality of lung cancer, the Chinese population standardized rate (ASR China), the world population standardized rate (ASR world), the age specific morbidity and mortality, and the composition and rank of lung cancer in all malignant tumors were calculated respectively. The Joinpoint regression was performed to calculate the average annual percentage changes (AAPC) and 95% CI for incidence/mortality of lung cancer between 2006 and 2015. Results Between 2006 and 2015, 4 209 new lung cancer cases were reported in Dafeng District, with the incidence of 58.13/105 and ASR China incidence of 33.44/105, accounting for 18.80% of all malignant tumors. It was reported that 3 848 cases died of lung cancer in the same period in Dafeng District, with the mortality of 53.15/105 and ASR China mortality of 30.17/105, accounting for 22.69% of all malignant tumor deaths. Both the incidence and mortality of lung cancer ranked the first place in all malignant tumors. The incidence and mortality, and ASR China incidence and mortality were all higher in males than those in females. In the past 10 years, the ASR China incidence and ASR China mortality of lung cancer in Dafeng District showed no significant changing trend (P>0.05), except for the ASR China mortality in males. Conclusion In Dafeng District, the incidence and mortality of lung cancer rank the first place in all malignant tumors. The incidence and mortality in whole population of Dafeng District show no significant change; therefore, the control and prevention program focusing on lung cancer still should be strengthened.