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Explorations on risk profiles for overweight and obesity in 9501 preschool-aged children
Institution:1. Graduate School, Beijing University of Chinese Medicine, Beijing, China;2. Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China;3. Department of Pediatrics, Changping District Maternal and Child Health Care Hospital, Beijing, China;4. Department of Pediatrics, Tangshan Maternal and Child Health Care Hospital, Hebei, China;5. International Medical Services, China–Japan Friendship Hospital, Beijing, China;6. Institute of Clinical Medical Sciences, China–Japan Friendship Hospital, Beijing, China
Abstract:BackgroundChildhood obesity places a major burden on global public health. We aimed to identify and characterize potential factors, both individually and jointly, in association with overweight and obesity in Chinese preschool-aged children.MethodsWe cross-sectionally recruited 9501 preschool-aged children from 30 kindergartens in Beijing and Tangshan. Overweight and obesity are defined according to the World Health Organization (WHO), International Obesity Task Force (IOTF), and China criteria.ResultsAfter multivariable adjustment, eating speed, sleep duration, birthweight, and paternal body mass index (BMI) were consistently and significantly associated with childhood overweight and obesity under three growth criteria at a significance level of 5%. Additional fast food intake frequency, maternal BMI, gestational weight gain (GWG) and maternal pre-pregnancy BMI were significant factors for overweight (WHO criteria) and obesity (both IOTF and China criteria). Importantly, there were significant interactions between parental obesity and eating speed for childhood obesity. Finally, for practical reasons, risk nomogram models were constructed for childhood overweight and obesity based on significant factors under each criterion, with good prediction accuracy.ConclusionOur findings indicated a synergistic association of lifestyle, fetal and neonatal, and family-related factors with the risk of experiencing overweight and obesity among preschool-aged children.
Keywords:Childhood overweight and obesity  Preschool-aged children  Risk profile  Interaction  Nomogram
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