钢铁工人血常规指标及尿酸水平与代谢综合征发病风险的相关性

目的研究钢铁工人血常规指标和尿酸水平与代谢综合征(MS)的关联。方法采用病例对照研究方法,选取内蒙古某钢铁企业接触噪声和高温危害因素的男性作业人员607人作为接害组,该企业不接触噪声与高温的行政和管理岗位的男性作业人员312人作为对照组。采集两组血标本,检测血常规和尿酸水平,分析接害组与对照组血常规指标白细胞计数(WBC)、红细胞计数(RBC)、血小板计数(PLT)、红细胞分布宽度(RDW)及血红蛋白含量(Hb)]和尿酸水平(UA)与MS的相关性。结果接害组和对照组间吸烟、饮酒、腰围(WC)、收缩压(SBP)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FPG)、WBC、RBC、PLT、Hb、RDW、体质量指数(BMI)及UA方面比较差异均有统计学意义(均P<0.05)。接害组MS总体患病率为39.04%,高于对照组的23.08%,差异有统计学意义(P<0.05)。两组MS患者和非MS患者WBC、RBC、PLT、RDW及UA比较差异均有统计学意义(均P<0.05)0多因素logistic回归分析发现WBC、RBC、RDW、PLT及UA是接害组MS的危险因素(均P<0.05)。结论钢铁工人MS患病率较高,红细胞计数增高、红细胞分布宽度增大及血小板计数升高是MS发生的危险因素。

Association of blood routine index and uric acid level with the risk of metabolic syndrome in iron and steel workers

Objective To study the correlation between blood routine indexes such as white blood cell count,red blood cell count,red blood cell distribution width,platelet count and uric acid level in iron and steel workers and the incidence of Metabolic Syndrome(MS).Methods A case-control study was conducted to select 607 male workers exposed to noise and high temperature hazards in an iron and steel enterprise in Inner Mongolia as the exposure group and 312 male workers in administrative and management positions who were not exposed to noise and high temperature as the control group.Blood samples were collected to detect blood routine and uric acid levels.Hie correlation between blood routine indices and uric acid levek of iron and steel workers and the occurrence of Metabolic Syndrome in exposed group and control group was analyzed according to whether they suffered from MS.Results The incidence of MS in the injured group was higher than that in the control group,with statistical significance(P<0.05).Compared with non-MS patients,the white blood cell count,red blood cell count,red blood cell distribution width,platelet count and senim inic acid levels in MS patients were all increased,and the difference was statistically significant(P<0.05).The total prevalence of the exposed group was 39.04%,which was higher than 23.08%in the control gronp.The difference was statistially significant.In the injured group,white blood cell count,red blood cell distribution width,platelet count and serum increased cell count,erythrocyte count,platelet count,serum uric acid level and erythrocyte distribution width increased the risk of MS.Increased erythrocyte count,platelet count and erythrocyte distribution width increased the risk of MS in the control group(P<0.05).Conclusion Hie prevalence of metabolic syndrome in iron and steel workers is higher than that in the general population.Increased red blood cell count,increased red blood cell distribution width and increased platelet count are risk factoio for MS.