| 高效抗逆转录病毒治疗艾滋病方案的效果评价 |
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| 引用本文： | 郑锦雷,杨介者,徐云,陈钢.高效抗逆转录病毒治疗艾滋病方案的效果评价[J].浙江预防医学,2010,22(1):5-7. |
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| 作者姓名： | 郑锦雷 杨介者 徐云 陈钢 |
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| 作者单位： | 浙江省疾病预防控制中心,浙江,杭州,310051 |
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| 摘 要： | 目的评价目前高效抗逆转录病毒治疗(HAART)方案的疗效,为以后的治疗方案提供参考。方法应用国家免费提供的抗病毒治疗药品,对符合治疗条件的艾滋病病毒(HIV)感染者/艾滋病(AIDS)病例进行规范的抗病毒治疗,并检测病例的病毒载量和淋巴细胞。结果治疗1～12个月,治疗病例CD4+T淋巴细胞计数呈明显上升趋势,均值为266.2;12个月之后,CD4+T淋巴细胞计数相对稳定,均值为353.1。治疗12个月前后,其差异具有统计学意义(P0.05)。治疗1～7个月,病例病毒载量计数呈明显下降趋势;治疗7个月之后,病例病毒载量计数相对变化较为稳定。治疗7个月前后,其差异有显著的统计学意义(P0.01)。结论浙江省艾滋病例在接受抗病毒治疗1年后,治疗效果明显,病例状态持续稳定。
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| 关 键 词： | 艾滋病 高效抗逆转录病毒治疗 效果 临床评价 |
Evaluation on the Highly Active Antiretroviral Therapy among People with HIV/AIDS |
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| ZHENG Jin-lei,YANG Jie-zhe,XU Yun,et al..Evaluation on the Highly Active Antiretroviral Therapy among People with HIV/AIDS[J].Zhejiang Journal of Preventive Medicine,2010,22(1):5-7. |
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| Authors: | ZHENG Jin-lei YANG Jie-zhe XU Yun |
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| Institution: | ZHENG Jin-lei,YANG Jie-zhe,XU Yun,et al. The Center for Disease Control , Prevention of Zhejiang province,Hangzhou,Zhejiang,310051,China. |
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| Abstract: | Objective To evaluate the curative effect of highly active antiretroviral therapy (HAART)and provide scientific evidence for the further use. Methods Each individual with HIV/AIDS was offered standardized antiretroviral drugs free of charge by government. Then HIV viral loads and CD + 4 T of each subject were detected periodically. Result During the first 12 months of HAART,the level of CD + 4 T in AIDS cases increased markedly and was 266.2. After 12 months,the level of CD + 4 T kept steady with an average... |
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| Keywords: | HIV/AIDS Highly active antiretroviral therapy (HAART) Effectiveness Clinical evaluation |
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