| 益生菌对实验性炎症性肠病的肠屏障与微生态影响研究进展 |
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| 引用本文： | 陈红旗,秦环龙.益生菌对实验性炎症性肠病的肠屏障与微生态影响研究进展[J].肠外与肠内营养,2008,15(2):123-128. |
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| 作者姓名： | 陈红旗 秦环龙 |
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| 作者单位： | 上海交通大学附属第六人民医院外科,上海,200233 |
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| 摘 要： | 炎症性肠病(IBD)的病因至今未明.近10年来,随着多种IBD动物模型的陆续开发,使得对益生菌治疗作用的研究得以广泛开展.诸多实验研究表明,益生菌对多种IBD动物模型的炎性症状均有明显地改善作用,益生菌的这种作用可能与其抑制肠道致病菌、增强肠屏障功能、调节肠道黏膜免疫反应、降解肠道内在或外来的致病抗原等有关.
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| 关 键 词： | 益生菌 炎症性肠病 肠道微生态 肠屏障 |
| 文章编号： | 1007-810X(2008)02-0123-06 |
| 修稿时间： | 2007年11月28 |
Advances in the effect of probiotics on gut barrier and microflora of experimental inflammatory bowel diseases |
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| CHEN Hong-qi,QIN Huan-long.Advances in the effect of probiotics on gut barrier and microflora of experimental inflammatory bowel diseases[J].Parenteral & Enteral Nutrition,2008,15(2):123-128. |
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| Authors: | CHEN Hong-qi QIN Huan-long |
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| Institution: | CHEN Hong-qi reviewing,QIN Huan-long checking(Department of Surgery,the Sixth People\'s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China) |
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| Abstract: | The aetiology of inflammatory bowel diseases(IBD) is still unknown at the present time.However,along with more and more experimental models of IBD developed in recent ten years,the therapeutic effect of probiotics on IBD and the possible mechanisms were widely explored.A lot of experiments have shown that probiotics administration can significantly ameliorate the IBD in many kinds of animal models and this beneficial effect of probiotics may be associated with inhibiting microbial growth,enhancing gut-barri... |
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| Keywords: | Probiotics Inflammatory bowel disease Intestinal microflora Gut barrier |
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