低热量肠外营养加生长激素对严重应激和重度营养不良病人的治疗体会

目的：观察生长激素加强危重病人应用全肠外营养支持的效果。方法：对严重应激（７例）和重度营养不良（９例）共１６例病人采用低热量肠外营养加重组生长激素联合治疗，并与仅用ＴＰＮ治疗的同类病人作对照研究，治疗后分别测定体重、血清白蛋白，前白蛋白和转铁蛋白及免疫球蛋白，计算氮平衡，观察精神状态。结果：治疗组比对照组在氮平衡、前白蛋白和转铁蛋白有明显改善（Ｐ＜０．０１），血清白蛋白，免疫球蛋白亦有明显增高（Ｐ＜０．０５），精神状态普遍较好，获得了较好的临床疗效。结论：低热量肠外营养加重组生长激素联合治疗是机体病理状态下一种较为理想的营养支持方法

The combined use of hypocaloric parenteral nutrition growth hormone in patients with severe stress and malnutrition

Objectives:To observe the role of recombinant human growth hormone(rhGH) in enhancing nutritional support in critically ill patients. Methods:Sixteen patiens(7 cases with severe stress and 9 cases with severe malnutrition) were treated with hypocaloric parenteral nutrition(hPN) and rhGH and compared with patients who received only standard total parenteral nutrition.The body weight,serum albumin,prealbumin,transferrin,immunoglobins and nitrogen balance were measured. Results:Positive nitrogen balance,prealbumin,transferrin,serum albumin and immunoglobins increased more obviously in combined group than those in controlled group. Conclusions:The use of hypocaloric parenteral nutrition combined with rhGH is helpful for nutrition surport in critically ill patients.