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藏药“大骨节Ⅰ号”治疗大骨节病的临床观察
引用本文:刘丽军,张晓慧,康龙丽,马利锋,崔海燕,胡抗,陈锋,扎西桑珠,龚宏强,郭敏,李小龙,陈文玲,贺学,杨凤英.藏药“大骨节Ⅰ号”治疗大骨节病的临床观察[J].国外医学:医学地理分册,2011,32(4):257-260.
作者姓名:刘丽军  张晓慧  康龙丽  马利锋  崔海燕  胡抗  陈锋  扎西桑珠  龚宏强  郭敏  李小龙  陈文玲  贺学  杨凤英
作者单位:1. 西藏民族学院医学院,高原环境与疾病相关基因研究重点实验室,生命科学基础实验室,陕西咸阳712082
2. 西藏地方病防治研究所,西藏拉萨,850000
3. 西藏拉萨市卫生局,西藏拉萨,850000
基金项目:科技部科技支撑计划项目,教育部重点项目,国家民委项目
摘    要:目的 观察大骨节Ⅰ号方丸剂治疗大骨节病的临床疗效.方法 选择大骨节病患者187例,随机分为3组:治疗组70例、对照组A 67例、对照组B50例,分别给予口服大骨节Ⅰ号方丸剂、布洛芬缓释胶囊、维生素C片.以上各组均连续服药3个月后观察疗效,并随访观察半年.以国家“大骨节病治疗效果判定标准(Ws/T79-1996)”和...

关 键 词:大骨节病  大骨节Ⅰ号方  治疗

Clinical efficacy observation of Tibet medicine DaGuJie I formalution on Kashin-Beck disease
LIU Li-jun,ZHANG Xiao-hui,KANG Long-li,MA Li-feng,CUI Hai-yan,HU Kang,CHEN Feng,ZAXI Sang-zhu,GONG Hong-qiang,GUO Min,LI Xiao-long,CHEN Wen-ling,HE Xue,YANG Feng-ying.Clinical efficacy observation of Tibet medicine DaGuJie I formalution on Kashin-Beck disease[J].Foreign Medical Sciences(Section of Medgeography),2011,32(4):257-260.
Authors:LIU Li-jun  ZHANG Xiao-hui  KANG Long-li  MA Li-feng  CUI Hai-yan  HU Kang  CHEN Feng  ZAXI Sang-zhu  GONG Hong-qiang  GUO Min  LI Xiao-long  CHEN Wen-ling  HE Xue  YANG Feng-ying
Institution:1. Key Laboratory of High Altitude Environment and Genes Related to Diseases of Tibet Autonomous Region; Laboratory of Life Science Base; School of Medicine, Tibet Nationality University, Xianyang Shaanxi 712082, Chinas2. Tibet Institute of Endemic Disease Control, Lassa 850000; 3. Lassa City Health Bureau of Tibet Autonomous Region, Lassa 850000, China)
Abstract:Objective To evaluate the clinical efficacy of Tibet medicine namely DaGuJie Ⅰ Formulation on Kashin-Beck disease. Methods 187 cases of Kashin-Beck disease were randomly divided into the treatment group, with patients treated by DaGuJie Ⅰ Formulation, the control group A, with 67 patients treated by Ibuprofen capsules and control group B with 50 patients treated by vitamin C. Its efficacy was observed by continuously taking the medicine 3 months, and six months follow-up observation for the long-term effect. The clinical efficacy was assessed ac- cording to "Kashin-Beck disease Treatment Criteria of China"(Ws/T79-1996)and international accepted Pain Visual Criteria (VAS). Result After three months treatment,the clinical effect of treatment group, control group A and control group B was 91.43%, 89.55% and 22% respectively. There was no statistical significance (P〉0.05)between treatment group and control group A; but it showed statistical significance (P〈0.05) between treatment group and control group B or control group A and control B. The clinical efficacy of treatment group and the control group A showed statistical significance compared with control group B after six months follow-up observation (P〈0.05). Conclusion DaGuJie Ⅰ Formulation significantly improved the clinical symptom of patients with Kashin- Beck disease, without toxic side effects.
Keywords:Kashin-Beck disease(KBD)  DaGuJie I Formulation  treatment
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